Candida albicans biofilms: development, regulation, and molecular mechanisms.
Candida albicans biofilms: development, regulation, and molecular mechanisms.
复制标题
DOI：
10.1016/j.micinf.2016.01.002
复制
发表时间：
2016-05
影响因子：
5.8
通讯作者：
Nobile CJ
中科院分区：
文献类型：
--
作者：
Gulati M;Nobile CJ
白色念珠菌的一个主要毒力属性是其形成生物膜的能力，生物膜是粘附在表面上的密集细胞群落。这些生物膜本质上对常规抗真菌治疗剂、宿主免疫系统和其他环境因素具有抗性，使得生物膜相关感染成为重大的临床挑战。本文就近年来有关C.白色念珠菌生物膜
A major virulence attribute of Candida albicans is its ability to form biofilms, densely packed communities of cells adhered to a surface. These biofilms are intrinsically resistant to conventional antifungal therapeutics, the host immune system, and other environmental factors, making biofilm-associated infections a significant clinical challenge. Here, we review current knowledge on the development, regulation, and molecular mechanisms of C. albicans biofilms.