AN IN-VITRO INVESTIGATION OF THE CARIOGENIC POTENTIAL OF ORAL STREPTOCOCCI
AN IN-VITRO INVESTIGATION OF THE CARIOGENIC POTENTIAL OF ORAL STREPTOCOCCI
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DOI：
10.1016/0003-9969(94)90134-1
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发表时间：
1994-07-01
影响因子：
3
通讯作者：
STEPHEN, KW
中科院分区：
文献类型：
--
作者：
CHESTNUTT, IG;MACFARLANE, TW;STEPHEN, KW
虽然变形链球菌在龋齿病因学中的重要性是明确的，但许多研究已经描述了在没有变形链球菌的情况下龋齿的发展。本研究旨在评估戈登链球菌、链球菌、链球菌和链球菌的致龋潜力。血链球菌前庭球菌和粪肠球菌与链球菌的比较。变形链球菌和链球菌。sobrinus，使用最近描述的体外模型。在146 mM蔗糖溶液和粉末状羟基磷灰石的存在下，将每种物质孵育5 h，之后测量酸阴离子产生、钙释放和pH变化。每个物种都可能被分为三个组之一，E。粪链球菌、链球菌戈登氏链球菌血液显示低，链球菌。前庭中间型和链球菌。变形链球菌和链球菌。sobrinus体外致龋潜力高。该试验可用作筛选试验，以评估一系列细菌种属的潜在致龋性。
Whilst the importance of the mutans streptococci in the aetiology of dental caries is clear, a number of studies have described caries development in their absence. This investigation aimed to assess the cariogenic potential of Streptococcus gordonii, Strep. sanguis, Strep. vestibularis and Enterococcus faecalis in comparison with Strep. mutans and Strep. sobrinus, using a recently described in vitro model. In the presence of a 146 mM sucrose solution and powdered hydroxyapatite, each species was incubated for 5 h, after which acid anion production, calcium release and change in pH were measured. It was possible to assign each species to one of three groups, with E. faecalis, Strep. gordonii, Strep. sanguis exhibiting low, Strep. vestibularis intermediate, and Strep. mutans and Strep. sobrinus high in vitro cariogenic potential. This assay could be used as a screening test to assess the potential cariogenicity of a range of bacterial species.