Dedicated phantom tools using traceable 68Ge/68Ga point-like sources for dedicated-breast PET and positron emission mammography scanners
Dedicated phantom tools using traceable 68Ge/68Ga point-like sources for dedicated-breast PET and positron emission mammography scanners
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DOI：
10.1007/s12194-022-00692-0
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发表时间：
2023-01-09
影响因子：
1.6
通讯作者：
Hashimoto，Masatoshi
中科院分区：
文献类型：
--
作者：
Okamoto，Mio;Hasegawa，Tomoyuki;Hashimoto，Masatoshi
自21世纪初以来，已经引入了许多类型的正电子发射断层扫描（PET）扫描仪，专用于乳腺成像以诊断乳腺癌。然而，为全身PET扫描仪开发的常规性能评估方法不能用于此类设备。在这项研究中，我们开发了体模工具，用于评估正电子发射乳腺X射线摄影（PEM）和专用乳腺PET（dbPET）扫描仪的定量准确性，使用新的可追溯点样68 Ge/68 Ga源。PEM体模由一个丙烯酸立方体（100 × 100 × 40 mm）和三个点状源组成。dbPET体模包括一个丙烯酸圆柱体（ø 100 × 100 mm）和五个点状源。这些幻影被用于评估的基本反应的临床PEM和dbPET扫描仪在介质中的点状输入。结果表明，根据重建图像的感兴趣区域分析，获得了合理的恢复值。使用可追踪的68 Ge/68 Ga点状源开发的体模可用于评价PEM和dbPET扫描仪的物理特性。因此，它们提供了一种实用、可靠和通用的测量方案，用于评估使用常用密封源组的各种类型的PET扫描仪。
Since the early 2000s, many types of positron emission tomography (PET) scanners dedicated to breast imaging for the diagnosis of breast cancer have been introduced. However, conventional performance evaluation methods developed for whole-body PET scanners cannot be used for such devices. In this study, we developed phantom tools for evaluating the quantitative accuracy of positron emission mammography (PEM) and dedicated-breast PET (dbPET) scanners using novel traceable point-like68Ge/68Ga sources. The PEM phantom consisted of an acrylic cube (100 × 100 × 40 mm) and three point-like sources. The dbPET phantom comprised an acrylic cylinder (ø100 × 100 mm) and five point-like sources. These phantoms were used for evaluating the fundamental responses of clinical PEM and dbPET scanners to point-like inputs in a medium. The results showed that reasonable recovery values were obtained based on region-of-interest analyses of the reconstructed images. The developed phantoms using traceable68Ge/68Ga point-like sources were useful for evaluating the physical characteristics of PEM and dbPET scanners. Thus, they offer a practical, reliable, and universal measurement scheme for evaluating various types of PET scanners using common sets of sealed sources.