The role of Mitogen activated protein kinase (MAPK) in sperm functions
The role of Mitogen activated protein kinase (MAPK) in sperm functions
复制标题
DOI：
10.1016/j.mce.2009.05.009
复制
发表时间：
2010-01-27
影响因子：
4.1
通讯作者：
Naor, Zvi
中科院分区：
文献类型：
--
作者：
Almog, Tal;Naor, Zvi
附睾中成熟精子的产生包括以复杂方式激活MAPK级联。MAPKs被认为参与睾丸转录和细胞外质特化（ES）的调节。MAPKs还调节成熟精子的鞭毛运动、超活化和顶体反应。本文综述了MAPKs在精子发生和成熟精子中的作用。(C)2009爱思唯尔爱尔兰有限公司保留所有权利。
The generation of mature spermatozoa in the epididymis includes the activation of the MAPK cascade in a complex manner. MAPKs are thought to be involved in the regulation of transcription and ectoplasmic specialization (ES) in the testis. MAPKs also regulate mature spermatozoa flagellar motility, hyperactivation and the acrosome reaction. Here we review the current data regarding the functions of MAPKs in spermatogenesis and in mature spermatozoa. (C) 2009 Elsevier Ireland Ltd. All rights reserved.