Factors associated with impaired quality of life in younger and older adults with epilepsy
Factors associated with impaired quality of life in younger and older adults with epilepsy
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DOI：
10.1016/j.eplepsyres.2008.09.001
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发表时间：
2009-01-01
影响因子：
2.2
通讯作者：
Takeda, Masatoshi
中科院分区：
文献类型：
--
作者：
Canuet, Leonides;Ishii, Ryouhei;Takeda, Masatoshi
本研究的目的是权衡老年癫痫患者的心理状态、患者的人口统计学资料、癫痫相关因素和医学合并症与年轻人的相同参数，以确定最佳生活质量（QoL）预测因子。对146例癫痫定位相关患者进行成人癫痫生活质量量表（QOLIE-31）和Beck抑郁量表-II（BDI-II）。年轻人和老年人的QOLIE-31总分没有统计学差异。最好的QoL预测因子是BDI-II和癫痫发作频率，BDI-II的影响是癫痫发作频率的3倍以上。BDI-II还实质性预测了大多数QOLIE-31结构域。此外，癫痫持续时间与总体生活质量呈正相关，只有老年人。总之，在年轻和老年癫痫患者中，抑郁症状是生活质量最强的预测因子。然而，老年人似乎更能适应他们的慢性健康问题。(C)2008 Elsevier B. V.保留所有权利。
The purpose of this study is to weigh psychological state, patients' demographics, seizure-related factors, and medical comorbidity in older adults with epilepsy against the same parameters in younger adults in an attempt to identify best quality of life (QoL) predictors. The Quality of Life in Epilepsy Inventory for Adults (QOLIE-31) and the Beck Depression Inventory-II (BDI-II) were completed by 146 patients with localization-related epilepsy. There was no statistical difference in the QOLIE-31 total score between younger and older adults. Best QoL predictors were BDI-II and seizure frequency, with BDI-II providing more than 3 times the impact of seizure frequency. BDI-II also substantively predicted most QOLIE-31 domains. Additionally, epilepsy duration positively correlated with overall QoL only among older adults. In summary, in younger as well as older adult epilepsy patients, depressive symptoms emerge as the strongest predictor of QoL. However, older adults appear to adapt better to their chronic health problem. (C) 2008 Elsevier B.V. All rights reserved.