10-YEAR INCIDENCE OF CORONARY HEART-DISEASE IN THE HONOLULU HEART PROGRAM - RELATIONSHIP TO NUTRIENT INTAKE
10-YEAR INCIDENCE OF CORONARY HEART-DISEASE IN THE HONOLULU HEART PROGRAM - RELATIONSHIP TO NUTRIENT INTAKE
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DOI：
10.1093/oxfordjournals.aje.a113788
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发表时间：
1984-01-01
影响因子：
5
通讯作者：
TILLOTSON, J
中科院分区：
文献类型：
--
作者：
MCGEE, DL;REED, DM;TILLOTSON, J
对居住在瓦胡岛上的8000多名日本血统男子的营养素摄入量进行了测定。营养素测定是在1965-1968年间的初次检查中进行的。这份报告将营养素摄入量与初次检查后10年内发生冠心病的风险联系起来。与未患冠心病的男性相比，患有冠心病的男性平均摄入的热量、碳水化合物、淀粉和植物蛋白更低。患有冠心病的男性从蛋白质、脂肪、饱和脂肪酸和多不饱和脂肪酸中平均摄取的卡路里百分比也高于没有患冠心病的男性。与没有患冠心病的男性相比，这些男性从碳水化合物中摄取的平均卡路里百分比明显更低，而每1000卡路里的平均胆固醇摄入量更高。在包括年龄、收缩压、血清胆固醇、每天吸烟和体力活动指数在内的多变量分析中，碳水化合物、植物蛋白、饱和脂肪酸的卡路里百分比和多不饱和脂肪酸的卡路里百分比不再与发病率显著相关。
Nutrient intake was determined in over 8000 men of Japanese ancestry residing on the island of Oahu. Nutrient determination took place at the initial examination during the years 1965-1968. This report relates nutrient intake to the risk of developing coronary heart disease in the 10 yr subsequent to the initial examination. Men who developed coronary heart disease had a lower average intake of calories, carbohydrates, starch, and vegetable protein than men who remained free of coronary heart disease. Men who developed coronary heart diease also had a higher mean intake of percentage of calories from protein, fat, saturated fatty acids, and polyunsaturated fatty acids than men who remained free of coronary heart disease. These men also had a significantly lower mean percentage of calories from carbohydrates and a higher mean ingestion of cholesterol per 1000 calories than men who remained free of coronary heart disease. In multivariate analyses including age, systolic blood pressure, serum cholesterol, cigarettes smoked per day, and physical activity index, carbohydrates, vegetable protein, percentage of calories from saturated fatty acids, and percentage of calories from polyunsaturated fatty acids are no longer significantly related to incidence.