Assessing provider and racial/ethnic variation in response to the FDA antidepressant box warning
Assessing provider and racial/ethnic variation in response to the FDA antidepressant box warning
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DOI：
10.1111/1475-6773.13104
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发表时间：
2019-02-01
影响因子：
3.4
通讯作者：
Zaslavsky, Alan M.
中科院分区：
文献类型：
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作者：
Cook, Benjamin L.;Wang, Ye;Zaslavsky, Alan M.
引言2004年FDA箱警告引发了人们对服用抗抑郁药的青少年自杀念头增加的担忧后，白色青少年的抗抑郁药使用量减少，但黑人和拉丁裔青少年的抗抑郁药使用量略有增加。需要更好地了解导致这些差异的患者和提供者因素，以改善未来的风险警告传播。方法我们分析了2002-2006年来自四个州（CA，FL，NC和NY）的医疗补助索赔数据中5-17岁青少年的抗抑郁药处方。在多水平模型中，我们评估了提供者和患者层面对种族/民族抗抑郁药使用变化的贡献，并比较了提供者（>2/3）和小（> 2/3）对方框警告的反应。
Introduction After the 2004 FDA box warning raised concerns about increased suicidal ideation among youth taking antidepressants, antidepressant use decreased for White youth but slightly increased for Black and Latino youth. Better understanding of patient and provider factors contributing to these differences is needed to improve future risk warning dissemination. Methods We analyzed antidepressant prescriptions for youth aged 5-17 in 2002-2006 Medicaid claims data from four states (CA, FL, NC, and NY). In multilevel models, we assessed provider- and patient-level contributions to changes in antidepressant use by race/ethnicity and compared responses to the box warning between providers with large (>2/3) and small (