OBJECTIVE CLINICAL-ASSESSMENT OF MOTOR FUNCTION AFTER EXPERIMENTAL SPINAL-CORD INJURY IN RAT
OBJECTIVE CLINICAL-ASSESSMENT OF MOTOR FUNCTION AFTER EXPERIMENTAL SPINAL-CORD INJURY IN RAT
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DOI：
10.3171/jns.1977.47.4.0577
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发表时间：
1977-01-01
影响因子：
4.1
通讯作者：
TATOR, CH
中科院分区：
文献类型：
--
作者：
RIVLIN, AS;TATOR, CH
建立了一种评价实验性脊髓损伤后大鼠运动功能的新方法。该方法包括将动物放置在可调整以提供不同坡度的斜面上，然后评估该平面的最大角度，在该平面上动物可以保持其位置而不会摔倒。用该方法定量测定正常大鼠和脊髓切除大鼠的运动功能，结果一致显示两组间存在较大差异。该方法具有许多优点：飞机易于制造，成本低；该检测具有快速、无创、重复性好、一致性好等特点。
A new method was developed for the clinical assessment of motor function in rats after experimental spinal cord injury. The method consisted of placing the animal on an inclined plane which can be adjusted to provide a slope of varying grade, and then assessing the maximum angle of the plane at which the animal can maintain its position without falling. The method was used to quantitate motor function in normal rats and rats subjected to myelectomy, and consistently showed major differences between the 2 groups. The method had many positive features: the plane was easy to construct and of low cost; and the test was rapid, non-invasive, repeatable and consistent.