Zincate-type enolate for radical α-trifluoromethylation
Zincate-type enolate for radical α-trifluoromethylation
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DOI：
10.1016/j.tetlet.2007.10.041
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发表时间：
2007-12-10
影响因子：
1.8
通讯作者：
Mikami, Koichi
中科院分区：
文献类型：
--
作者：
Tomita, Yuichi;Ichikawa, Yoshiyuki;Mikami, Koichi
酮锌酸盐型烯醇化物可用于自由基三氟甲基化，用于α-CF 3-酮，特别是环戊酮的一般合成。二乙基锌与烯醇化锂的加成反应是制备锌酸盐型烯醇化锂的关键。(c)2007爱思唯尔有限公司版权所有。
Ketone zincate-type enolates can be applied to radical trifluoromethylation for the general synthesis of alpha-CF3-ketones, cyclopentanones in particular. The addition of diethylzinc to lithium enolates is the key in the preparation of the zincate-type enolates for efficient radical trifluoromethylation. (c) 2007 Elsevier Ltd. All rights reserved.