Are human taste thresholds similar on the right and left sides of the tongue?
Are human taste thresholds similar on the right and left sides of the tongue?
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DOI：
10.1093/chemse/26.7.875
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发表时间：
2001-09-01
期刊：
影响因子：
3.5
通讯作者：
Breslin, PAS
中科院分区：
文献类型：
--
作者：
McMahon, DBT;Shikata, H;Breslin, PAS
人类的舌头是一个相对对称的解剖结构，通常被认为在两侧的功能等同。这个假设的实验评估是复杂的事实，心理物理测量往往会有很大的不同测试会话。为了解决功能性偏侧，我们确定了检测阈值的六个右手和六个左手科目糖精钠，氯化钠，柠檬酸和盐酸奎宁。五对交织，左，右单侧阈值，获得每个味觉刺激在12个科目（n = 480个单独的阈值）。在大多数情况下，基于多次测量的平均灵敏度被发现是横向对称的，然而，我们观察到一些情况下的横向不对称的一般和化合物的特定灵敏度。阈值被发现有很大的不同会话，一致的重测变异先前报告的全口阈值。我们的结论是，味觉阈值敏感性是相当的，对大多数人的左，右前舌。然而，考虑到这一规则的偶尔例外情况，建议在任何实验或临床测试方案中采用平衡设计，其中治疗不对称地应用于舌头。
The human tongue is a relatively symmetrical anatomical structure and is generally assumed functionally equivalent on both sides. Experimental evaluation of this assumption is complicated by the fact that psychophysical measurements tend to vary considerably across testing sessions. To address functional laterality, we determined the detection thresholds of six right-handed and six left-handed subjects for Na saccharin, NaCl, citric acid and quinine HCl. Five pairs of interwoven, left and right unilateral thresholds were obtained for each taste stimulus in 12 subjects (n = 480 separate thresholds). In most cases mean sensitivity based on multiple measurements was found to be laterally symmetrical, however, we observed a few cases of lateral asymmetry of both general and compound-specific sensitivity. Threshold values were found to vary considerably across sessions, consistent with the test-retest variability previously reported for whole mouth thresholds. We conclude that taste threshold sensitivity is equivalent on the left and right anterior tongue for most individuals. Given the occasional exceptions to this rule, however, it is advisable to employ a counterbalanced design for any experimental or clinical testing protocol in which treatments are applied asymmetrically to the tongue.