Rational design and application of molecularly imprinted sol-gel polymer for the electrochemically selective and sensitive determination of Sudan I.
Rational design and application of molecularly imprinted sol-gel polymer for the electrochemically selective and sensitive determination of Sudan I.
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DOI：
10.1016/j.talanta.2011.01.047
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发表时间：
2011-04
期刊：
影响因子：
6.1
通讯作者：
Shizhen Chen;Dan Du;Jing Huang;Aiqing Zhang;Haiyang Tu;Aidong Zhang
中科院分区：
文献类型：
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作者：
Shizhen Chen;Dan Du;Jing Huang;Aiqing Zhang;Haiyang Tu;Aidong Zhang
基于合理设计的金纳米粒子（AuNPs）分子印迹溶胶-凝胶聚合物，建立了一种特异、灵敏测定苏丹红I的电化学方法。通过将苏丹红I与3-氨丙基三乙氧基硅烷、正硅酸乙酯、壳聚糖和金纳米粒子混合，然后共聚和萃取模板分子，制备了苏丹红I印迹溶胶-凝胶。采用扫描电镜和傅里叶变换红外吸收光谱对杂化膜进行了表征，并将其用于线性扫描伏安法（LSV）测定水/乙醇溶液中的苏丹红I。LSV的反应表现出高灵敏度和选择性，区别于苏丹红I类似物。在最佳实验条件下，苏丹红I浓度在0.1×10− 7 ~ 1.0×10− 5 M范围内与LSV峰电流呈线性关系，检出限为2.0×10− 9 M。该策略通常适用于开发灵敏的，选择性的，而且，可重复使用的电化学传感器，用于定量测定电活性物质。
An electrochemical strategy on the basis of rationally designed molecularly imprinted sol–gel polymer embedded with gold nanoparticles (AuNPs) is developed for the specific and sensitive determination of Sudan I. The rationally designed sensing Sudan I imprinted sol–gel was prepared by mixing Sudan I with 3-aminopropyltriethoxysilane, tetraethoxysilane, chitosan, and AuNPs, followed by copolymerization and extraction of the template molecules. The hybrid forming membrane was characterized by SEM and FTIR-ATR, and used for the linear sweep voltammetric (LSV) determination of Sudan I in water/ethanol solutions. The LSV responses exhibited high sensitivity and selectivity, as discriminated from Sudan I analogues. Under optimal experimental conditions, LSV peak currents were linearly proportional to the concentrations of Sudan I in the range from 0.1×10−7to 1.0×10−5M, with a detection limit of 2.0×10−9M. The strategy is generally applicable in developing sensitive, selective, and moreover, reusable electrochemical sensors for quantitative determination of electroactive species.