Configuration of some para-substituted benzhydrols
Configuration of some para-substituted benzhydrols
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一些对位取代的二苯甲醇的构型
DOI：
10.1021/jo00360a049
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发表时间：
1986
影响因子：
3.6
通讯作者：
H. Mosher
中科院分区：
文献类型：
--
作者：
Biqi Wu;H. Mosher
1，2-二溴-1，2-二苯基-乙烷的内消旋和dl对异构体如前所述制备;内消旋，mp249 -251 ℃（lit.26254 -255 ℃ dec）; dl，mp 108-109 ℃（lit.27mp110 -111 ℃）。所报道的3 JH/h偶联在WP-200-SY中获得，（Department de Química Orgánica，Universidad Autónoma de马德里，西班牙）或WM-250（UNO）Bruker仪器从1H-NMR光谱中，观察以5.48（CDC 1），5.69（CD 3 OD），dl对为5.87（丙酮-dg）或6.10（Me 2SO-d 6）ppm，内消旋异构体为5.48（CDC 13）ppm。在实验误差范围内，在正常强信号两侧观察到的两个双峰之间的距离（Hz）是相同的，Vc_h偶联（约为100 Hz）。在CHBrCHBr碳信号的质子耦合13 C光谱（CDC 13）中观察到内消旋异构体的56.2 ppm和dl对的59.1 ppm。这项工作得到了NSF Grant CHE-8314169的支持。
The meso and dl pair isomers of 1, 2-dibromo-l, 2-diphenyl-ethane were prepared as previously described; meso, mp 249-251 C (lit. 26 254-255 C dec); dl, mp 108-109 C (lit. 27 mp 110-111 C). The reported 3JH/h couplings were obtained in either a WP-200-SY (Department de Química Orgánica, Universidad Autónoma de Madrid, Spain) or a WM-250 (UNO) Bruker instrument from the 1H-NMR spectra, looking at the 13C satellites of the 12CH signal centered at 5.48 (CDC1), 5.69 (CD3OD), 5.87 (acetone-dg) or 6.10 (Me2SO-d6) ppm for the dl pair and 5.48 (CDC13) ppm for the meso isomer. The distance in Hzbetween the two observed doublets flanking the normal, intense signal was identical, within the experimental error, with theVc_h coupling (ca. 156.5 Hz for both isomers) observed in the proton coupled 13C spectra (CDC13) for the CHBrCHBr carbon signal 56.2 ppm for the meso isomer and at 59.1 ppm for the dl pair.Acknowledgment. This work was supported by NSF Grant CHE-8314169.