Diabetic kidney disease: a clinical update from Kidney Disease: Improving Global Outcomes.

Diabetic kidney disease: a clinical update from Kidney Disease: Improving Global Outcomes.
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DOI:
10.1038/ki.2014.128
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发表时间:
2015-01
影响因子:
19.6
通讯作者:
--
中科院分区:
医学1区
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--
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糖尿病(DM)的发病率和患病率在全世界持续急剧增长,主要是由于2型DM(T2 DM)的增加。虽然糖尿病和高血压管理的改善降低了糖尿病患者发展为慢性肾病(CKD)和进展为终末期肾病(ESRD)的比例,但糖尿病患者的绝对增加将对透析和移植需求产生重大影响。本次KDIGO会议讨论了糖尿病伴CKD患者管理中的一些有争议的领域,包括通过测量白蛋白尿和估计肾小球滤过率(eGFR)筛查CKD的各个方面;定义治疗结局; CKD患者和ESRD患者的血糖管理;高血压目标和管理,包括肾素-血管紧张素-醛固酮系统阻滞剂;以及脂质管理。
The incidence and prevalence of diabetes mellitus (DM) continue to grow dramatically throughout the world, due primarily to the increase in type 2 DM (T2DM). Although improvements in DM and hypertension management have reduced the proportion of diabetic individuals who develop chronic kidney disease (CKD) and progress to end-stage renal disease (ESRD), the sheer increase in people developing DM will have a major impact on dialysis and transplant needs. This KDIGO conference addressed a number of controversial areas in the management of DM patients with CKD, including aspects of screening for CKD with measurements of albuminuria and estimated glomerular filtration rate (eGFR); defining treatment outcomes; glycemic management in both those developing CKD and those with ESRD; hypertension goals and management, including blockers of the renin-angiotensin-aldosterone system; and lipid management.
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