Analysis of the baseline survey on the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) in holdings with breeding pigs, in the EU, 2008 Part A: MRSA prevalence estimates
Analysis of the baseline survey on the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) in holdings with breeding pigs, in the EU, 2008 Part A: MRSA prevalence estimates
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DOI：
10.2903/j.efsa.2009.1376
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发表时间：
2009-11-01
期刊：
影响因子：
3.3
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中科院分区：
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耐甲氧西林金黄色葡萄球菌（MRSA）是公共卫生的主要问题。MRSA谱系ST 398被认为是与猪接触的人的职业危害，偶尔会被引入医院。这项初步的欧盟范围内的MRSA基线调查于2008年在种猪群中进行。来自24个欧盟成员国的1，421个主要饲养和销售种猪的养殖场（养殖场）和3，176个主要饲养种猪和销售用于育肥或屠宰的猪的养殖场（生产场）被纳入调查。另外，两个不属于欧洲联盟的国家参加了调查。从控股公司收集的合并灰尘样本进行了MRSA测试，所有分离株进行了分型的SPA分型和有关属于MRSA ST 398分类。调查结果表明，MRSA在一些成员国的种猪群中普遍检出，而在其他成员国的流行率较低。七个会员国在调查的库存中没有发现任何MRSA。欧盟MRSA阳性养殖群的患病率为14.0%，各成员国的患病率从0%到46.0%不等。欧盟MRSA阳性生产库存的流行率为26.9%，而成员国的流行率从0%到51.2%不等。MRSA ST 398是鉴定的主要MRSA谱系，覆盖92.5%的MRSA分离株。在六个成员国检测到不属于ST 398的MRSA分离株。分离出一组不同的MRSA spa型，尽管t011 spa型是迄今为止最主要的类型。在被调查的猪群中也检测到不属于人类医学中描述的ST 398的MRSA spa型。建议监测食用动物种属中的MRSA，并调查猪中非ST 398 MRSA结果对人类健康的重要性。
Methicillin-resistant Staphylococcus aureus (MRSA) is a major concern for public health. The MRSA lineage ST398 has been recognised as an occupational hazard for people in contact with pigs and it can occasionally be introduced into hospitals. This preliminary European Union-wide baseline survey on MRSA was conducted in 2008 in holdings with breeding pigs. A total of 1,421 holdings housing and selling mainly breeding pigs (breeding holdings), and 3,176 holdings housing breeding pigs and selling mainly pigs for fattening or slaughter (production holdings) from 24 European Union Member States were included in the survey. Also, two countries not belonging to the European Union participated in the survey. Pooled dust samples collected from the holdings were tested for MRSA and all isolates were typed by spa-typing and classified in relation to belonging to MRSA ST398. The survey results indicate that MRSA was commonly detected in holdings with breeding pigs in some Member States, while in other Member States prevalence was low. Seven Member States did not detect any MRSA in the surveyed holdings. The European Union prevalence of MRSA positive breeding holdings was 14.0%, and the prevalence varied from 0% to 46.0% among the Member States. The European Union prevalence of MRSA positive production holdings was 26.9%, while in Member States prevalence varied from 0% to 51.2%. MRSA ST398 was the predominant MRSA lineage identified, covering 92.5% of the MRSA isolates. MRSA isolates not belonging to ST398 were detected in six Member States. A varying set of MRSA spa-types was isolated, although the t011 spa-type was by far the most dominant type. MRSA spa-types not belonging to ST398 described in human medicine were also detected among the surveyed pig holdings. Monitoring of MRSA in food producing animal species as well as investigations of human health importance of the non-ST398 MRSA findings in pigs are recommended.