Smoking during Pregnancy and Adverse Birth and Maternal Outcomes in California, 2007 to 2016
Smoking during Pregnancy and Adverse Birth and Maternal Outcomes in California, 2007 to 2016
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DOI：
10.1055/s-0039-1693689
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发表时间：
2020-11-01
影响因子：
2
通讯作者：
Basford, Kaye E.
中科院分区：
文献类型：
--
作者：
Ratnasiri, Anura W. G.;Gordon, Lauren;Basford, Kaye E.
目的 本研究旨在确定孕产妇吸烟与不良分娩和孕产妇结局之间的关联。研究设计 这是一项为期 10 年的基于人群的回顾性队列研究，包括加利福尼亚州 4,971,896 名居民的出生。将吸烟者与不吸烟者的妊娠结局进行比较。还调查了在怀孕前或怀孕期间停止吸烟的妇女的结局。 结果 与不吸烟者的婴儿相比，怀孕期间吸烟的妇女所生的婴儿出现低出生体重 (LBW) 和小于胎龄 (SGA) 的可能性高出一倍，极低出生体重 (VLBW) 或早产 (PTB) 的可能性高 57%，极 PTB 的可能性高 59%。研究期间，吸烟者和非吸烟者所生婴儿的LBW和PTB率以及SGA百分比之间的差距显着扩大。 结论 怀孕期间吸烟与不良分娩和产妇结局的风险显着增加有关，并且在此期间吸烟者和非吸烟者所生婴儿的LBW、PTB和SGA率差异加大。怀孕前甚至妊娠前三个月戒烟可显着降低婴儿低出生体重、PTB、SGA 的风险以及母亲剖宫产的风险。
Objective This study aimed to determine associations between maternal cigarette smoking and adverse birth and maternal outcomes.Study Design This is a 10-year population-based retrospective cohort study including 4,971,896 resident births in California. Pregnancy outcomes of maternal smokers were compared with those of nonsmokers. The outcomes of women who stopped smoking before or during various stages of pregnancy were also investigated.Results Infants of women who smoked during pregnancy were twice as likely to have low birth weight (LBW) and be small for gestational age (SGA), 57% more likely to have very LBW (VLBW) or be a preterm birth (PTB), and 59% more likely to have a very PTB compared with infants of nonsmokers. During the study period, a significant widening of gaps developed in both rates of LBW and PTB and the percentage of SGA between infants of maternal smokers and nonsmokers.Conclusion Smoking during pregnancy is associated with a significantly increased risk of adverse birth and maternal outcomes, and differences in rates of LBW, PTB, and SGA between infants of maternal smokers and nonsmokers increased during this period. Stopping smoking before pregnancy or even during the first trimester significantly decreased the infant risks of LBW, PTB, SGA, and the maternal risk for cesarean delivery.