Disease burden of COPD in China: a systematic review.
Disease burden of COPD in China: a systematic review.
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DOI：
10.2147/copd.s161555
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发表时间：
2018
影响因子：
2.8
通讯作者：
Zhang L
中科院分区：
文献类型：
--
作者：
Zhu B;Wang Y;Ming J;Chen W;Zhang L
慢性阻塞性肺病（COPD）是全球疾病负担的主要原因之一。本系统评价的目的是量化中国COPD的疾病负担，并确定该疾病的危险因素。纳入综述的研究数量为47项，平均质量评估得分为7.70分（满分10分）。中国不同省市报告的COPD患病率在1.20%至8.87%之间。男性COPD患病率（7.76%）高于女性（4.07%）。农村患病率（7.62%）高于城市（6.09%）。中国COPD患者的诊断率为23.61%~ 30.00%。COPD患者接受门诊治疗的比例约为50%，而住院率介于8.78%和35.60%之间。烟草暴露和生物质燃料/固体燃料的使用被认为是COPD的两个重要危险因素。慢性阻塞性肺病是中国三大主要死因之一。COPD的直接医疗费用为72 ~ 3565美元/年，占当地人均年收入的33.33%~ 118.09%。最常用的生活质量（QoL）评估量表包括圣乔治呼吸问卷、气道问卷20、SF-36及其修订版。COPD患者的生活质量较非COPD患者差，COPD患者抑郁风险较高。在经济负担和QoL方面，中国的COPD负担较高。鉴于中国吸烟率高，以及对空气污染和烟雾的相当关注，需要采取对策改善疾病预防和管理，以减少COPD造成的疾病负担。
Chronic obstructive pulmonary disease (COPD) is one of the main contributors to the global burden of disease. The aim of this systematic review was to quantify the disease burden of COPD in China and to determine the risk factors of the disease. The number of studies included in the review was 47 with an average quality assessment score of 7.70 out of 10. Reported COPD prevalence varied between 1.20% and 8.87% in different provinces/cities across China. The prevalence rate of COPD was higher among men (7.76%) than women (4.07%). The disease was more prevalent in rural areas (7.62%) than in urban areas (6.09%). The diagnostic rate of COPD patients in China varied from 23.61% to 30.00%. The percentage of COPD patients receiving outpatient treatment was around 50%, while the admission rate ranged between 8.78% and 35.60%. Tobacco exposure and biomass fuel/solid fuel usage were documented as two important risk factors of COPD. COPD ranked among the top three leading causes of death in China. The direct medical cost of COPD ranged from 72 to 3,565 USD per capita per year, accounting for 33.33% to 118.09% of local average annual income. The most commonly used scales for the assessment of quality of life (QoL) included Saint George Respiratory Questionnaire, Airways Questionnaire 20, SF-36, and their revised versions. The status of QoL was worse among COPD patients than in non-COPD patients, and COPD patients were at higher risks of depression. The COPD burden in China was high in terms of economic burden and QoL. In view of the high smoking rate and considerable concerns related to air pollution and smog in China, countermeasures need to be taken to improve disease prevention and management to reduce disease burdens raised by COPD.