A reactor for high-throughput high-pressure nuclear magnetic resonance spectroscopy
A reactor for high-throughput high-pressure nuclear magnetic resonance spectroscopy
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DOI：
10.1063/1.4932676
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发表时间：
2015-10-01
影响因子：
1.6
通讯作者：
Landis, C. R.
中科院分区：
文献类型：
--
作者：
Beach, N. J.;Knapp, S. M. M.;Landis, C. R.
设计了一种用于高压气液反应的核磁共振监测反应器。威斯康星高压核磁共振反应堆（WiHP-NMRR）设计包括四个模块：具有钛管保持器的蓝宝石NMR管，其额定压力高达1000 psig（68 atm），温度范围为-90至90 ℃，气体循环系统，其在气体消耗或气体释放反应期间保持溶解气体的平衡浓度，能够在高压条件下向反应器中加入测量量的溶液的液体注射装置，以及能够在不从NMR仪器中取出的情况下清洁反应器的快速洗涤系统。WiHP-NMRR与商用10 mm NMR探头兼容。在WiHP-NMRR中进行的反应在整个反应时间过程中产生高质量、信息丰富的多核NMR数据，并具有快速的实验周转。(C)2015 AIP Publishing LLC.
The design of a reactor for operando nuclear magnetic resonance (NMR) monitoring of high-pressure gas-liquid reactions is described. TheWisconsin High Pressure NMR Reactor (WiHP-NMRR) design comprises four modules: a sapphire NMR tube with titanium tube holder rated for pressures as high as 1000 psig (68 atm) and temperatures ranging from -90 to 90 degrees C, a gas circulation system that maintains equilibrium concentrations of dissolved gases during gas-consuming or gas-releasing reactions, a liquid injection apparatus that is capable of adding measured amounts of solutions to the reactor under high pressure conditions, and a rapid wash system that enables the reactor to be cleaned without removal from the NMR instrument. The WiHP-NMRR is compatible with commercial 10 mm NMR probes. Reactions performed in the WiHP-NMRR yield high quality, information-rich, and multinuclear NMR data over the entire reaction time course with rapid experimental turnaround. (C) 2015 AIP Publishing LLC.