Urinary phytate in calcium oxalate stone formers and healthy people -: Dietary effects on phytate excretion

Urinary phytate in calcium oxalate stone formers and healthy people -: Dietary effects on phytate excretion
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DOI:
10.1080/003655900750016526
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发表时间:
2000-06-01
影响因子:
--
通讯作者:
Conte, A
Conte, A
中科院分区:
其他
文献类型:
--
作者:
Grases, F;March, JG;Conte, A

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对一组活性草酸钙结石患者的尿植酸值进行了研究,并与健康人的尿植酸值进行了比较。结石形成组的尿植酸值明显较低。缺乏抑制钙盐结晶的能力被认为是与钙结石形成有关的重要因素。低植酸排泄量可能是此类肾结石发生的重要危险因素。此外,还研究了日粮中添加植酸对尿液排泄的影响。显然,保持不含植酸的饮食显著减少了植酸盐的尿排出量(36小时后约为50%)。这证明了饮食中植酸盐在保持足够的尿液水平以允许有效抑制钙盐结晶从而防止肾结石形成方面的重要性。
The phytate urinary levels in a group of active calcium oxalate stone formers were studied and compared with those found in healthy people. Urinary phytate was significantly lower for stone formers. If deficit of the capacity to inhibit crystallization of calcium salts is considered an important factor related to calcium stone formation. the excretion of low phytate amounts could be an important risk factor in the development of this type of renal calculi. The influence of dietary phytate on urinary excretion was also studied. Clearly maintenance of a phytate-free diet significantly decreased the urinary excretion of phytate (about 50% after 36 h). This demonstrated the importance of dietary phytate in maintaining adequate urinary levels to permit effective crystallization inhibition of calcium salts and consequently preventing renal stone development.