Bilateral cerebellopontine angle lesions not always NF2: diagnostic pitfall
Bilateral cerebellopontine angle lesions not always NF2: diagnostic pitfall
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双侧桥小脑角病变并不总是 NF2：诊断陷阱
DOI：
10.3109/02688697.2011.603851
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发表时间：
2012
影响因子：
1.1
通讯作者：
M. Kamel
中科院分区：
文献类型：
--
作者：
A. Rao;A. Lawrie;P. Bodkin;J. Tighe;M. Kamel
双侧内耳道（IAC）肿瘤几乎完全与双侧前庭神经鞘瘤相关，很少有，如果有的话，可以模仿这种外观。我们报告一个非常罕见的病例，一位75岁的男士，他最初表现为双侧IAC肿瘤，后来被诊断为孤立的原发性中枢神经系统骨髓瘤，没有全身受累。这是一种非常罕见的表现，具有重要的诊断和治疗意义。他接受来那度胺和地塞米松联合治疗。治疗耐受性良好，但反应有限。虽然罕见，但转移应被视为IAC病变的鉴别诊断。
Abstract Bilateral internal auditory canal (IAC) tumours are almost exclusively associated with bilateral vestibular schwannomas, and there is very little, if anything, that can mimic this appearance. We present a very rare case of a 75-year-old gentleman who initially presented with bilateral IAC tumours and later diagnosed as an isolated primary CNS myeloma without systemic involvement. This is a very rare presentation and has important diagnostic and therapeutic implications. He was treated with a combination of lenalidomide and dexamethasone. The treatment was well tolerated but with limited response. Although rare, metastasis should be considered as a differential diagnosis of IAC lesions.