Exercise Increases 24-h Fat Oxidation Only When It Is Performed Before Breakfast.
Exercise Increases 24-h Fat Oxidation Only When It Is Performed Before Breakfast.
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DOI：
10.1016/j.ebiom.2015.10.029
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发表时间：
2015-12
期刊：
影响因子：
11.1
通讯作者：
Tokuyama K
中科院分区：
文献类型：
--
作者：
Iwayama K;Kurihara R;Nabekura Y;Kawabuchi R;Park I;Kobayashi M;Ogata H;Kayaba M;Satoh M;Tokuyama K
作为现代社会日益多样化的生活方式的一部分，人们选择锻炼的时间也有很大的差异。美国和日本最近的调查显示，在工作日，更多的人在晚上锻炼，而在上午或下午锻炼的人更少。当能量摄入与能量消耗相匹配(能量平衡状态)时，在餐后状态下进行的运动对超过24小时的累积脂肪氧化(24小时脂肪氧化)几乎没有影响。本研究探讨了只有在摄取后状态下，即早餐前，运动才能增加24小时脂肪氧化的可能性。使用代谢室对10名年轻的非肥胖男性进行了超过24小时的间接量热测试。受试者在早餐(早上)、午餐(下午)或晚餐(晚上)前(上午)、午餐(下午)或晚餐(晚上)前静坐(对照组)或进行60分钟的运动，最大摄氧量为50%。所有试验都设计为在24小时内实现能量平衡。根据输入(膳食消耗)和输出(氧化)之间的差异，估计相对于热量测量开始的能量和底物平衡的时间进程。只有在早餐前进行运动时，24小时以上的脂肪氧化才会增加(对照组，456±0.61；上午，717±0.44千卡/天；下午，446±0.57千卡；晚上，432±0.44千卡/天)。超过24小时的脂肪氧化与暂时性能量和碳水化合物缺乏的程度呈负相关。在能量平衡的条件下，只有在早餐前进行运动才会增加24小时的脂肪氧化。晨练后观察到的一过性碳水化合物缺乏，即糖原耗竭，可能是导致24小时脂肪氧化增加的原因之一。早餐前进行的运动会增加24小时的脂肪氧化。运动导致的瞬时能量不足提示增加24小时的脂肪氧化。摄食状态下的运动不会增加能量平衡状态下的24小时脂肪氧化。尿氮排泄量不受一天中锻炼时间的影响。使用代谢室对10名超过24小时的年轻男性进行了间接量热测定。受试者在早餐前、午餐后或晚餐后以50%的最大摄氧量进行静坐或60min的运动。所有试验都被设计成能量平衡的，即24小时内能量的摄入量和消耗是匹配的。当运动在午餐或晚餐后进行时，24小时的脂肪氧化与久坐的一天相似，即运动不会增加脂肪氧化。只有在早餐前进行锻炼时，24小时脂肪氧化增加，晨练后显著的一过性能量不足似乎刺激了24小时脂肪氧化。
As part of the growing lifestyle diversity in modern society, there is wide variation in the time of day individuals choose to exercise. Recent surveys in the US and Japan have reported that on weekdays, more people exercise in the evening, with fewer individuals exercising in the morning or afternoon. Exercise performed in the post-prandial state has little effect on accumulated fat oxidation over 24 h (24-h fat oxidation) when energy intake is matched to energy expenditure (energy-balanced condition). The present study explored the possibility that exercise increases 24-h fat oxidation only when performed in a post-absorptive state, i.e. before breakfast. Indirect calorimetry using a metabolic chamber was performed in 10 young, non-obese men over 24 h. Subjects remained sedentary (control) or performed 60-min exercise before breakfast (morning), after lunch (afternoon), or after dinner (evening) at 50% of VO2max. All trials were designed to be energy balanced over 24 h. Time course of energy and substrate balance relative to the start of calorimetry were estimated from the differences between input (meal consumption) and output (oxidation). Fat oxidation over 24 h was increased only when exercise was performed before breakfast (control, 456 ± 61; morning, 717 ± 64; afternoon, 446 ± 57; and evening, 432 ± 44 kcal/day). Fat oxidation over 24 h was negatively correlated with the magnitude of the transient deficit in energy and carbohydrate. Under energy-balanced conditions, 24-h fat oxidation was increased by exercise only when performed before breakfast. Transient carbohydrate deficits, i.e., glycogen depletion, observed after morning exercise may have contributed to increased 24-h fat oxidation. Exercise performed before breakfast increases 24 h fat oxidation. Exercise-induced transient energy deficit cues to increase 24 h fat oxidation. Exercise in fed state doesn't increase 24 h fat oxidation in energy-balanced condition. Urinary N2 excretion was not affected by time of the day when exercise was performed. Indirect calorimetry using a metabolic chamber was performed in 10 young men over 24 h. Subjects remained sedentary or performed 60-min exercise before breakfast, after lunch or dinner at 50% of VO2max. All trials were designed to be energy balanced, i.e., intake and expenditure of energy over 24-h were matched. When exercise was performed after lunch or dinner, 24-h fat oxidation was similar to that of sedentary day, i.e. exercise didn't increase fat oxidation. Only when exercise was performed before breakfast, 24-h fat oxidation increased, and a significant transient energy deficit after morning exercise seems to stimulate 24-h fat oxidation.