Developmental and methylmercury effects on brain protein synthesis
Developmental and methylmercury effects on brain protein synthesis
复制标题
发育和甲基汞对脑蛋白质合成的影响
DOI：
10.1007/bf01056353
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发表时间：
1979
影响因子：
4
通讯作者：
E. Hupp
中科院分区：
文献类型：
--
作者：
Francine E. Joiner;E. Hupp
Sprague-Dawley rats (ages 1 to 21 days, alternate days) were chosen for study. Animals were injected with methylmercuric chloride (8 mg/kg IP); 12 hr later each animal was injected with uniformly labeled L-(14C)leucine, allowed 30 min for incorporation, and decapitated. Brains were analyzed for amounts of radioactivity incorporated into TCA precipitable protein. When compared to baseline curves for control animals, curves of treated animals were compressed overall and had age-dependent increases and decreases in rates of protein synthesis.
