Metastatic patterns in soft-tissue sarcomas.
Metastatic patterns in soft-tissue sarcomas.
复制标题
软组织肉瘤的转移模式。
作者：
M. Vezeridis;R. Moore;C. Karakousis
在242例复发性软组织肉瘤患者中，47.5%的患者最初复发的最常见部位是原发部位，38%的患者是肺部。在疾病的过程中，进一步复发涉及肺、骨、肝和脑。总生存率和复发后生存率受组织学类型的影响，这也影响复发部位。在局部复发的管理中，手术治疗的五年无病生存率为38%，而单纯放疗或化疗无效。局部复发的患者生存率明显高于其他器官复发的患者。无病间期是整个患者组和局部复发患者随后生存的重要预后指标。
In 242 patients with recurrent soft-tissue sarcomas, the most common sites of initial recurrence were the primary site in 47.5% of patients and the lungs in 38% of patients. Further recurrences in the course of the disease concerned the lungs, bones, liver, and brain. Total survival and survival after recurrence were influenced by the histologic type, which also affected the site of recurrence. In the management of local recurrence, a five-year disease-free survival rate of 38% was achieved with surgical treatment, while radiation or chemotherapy alone was ineffective. Local recurrences resulted in significantly higher survival rates than those involving other organs. The disease-free interval was a significant prognostic indicator of subsequent survival in the whole group of patients and among those with local recurrence.