Choreoathetoid movements in cocaine dependence

Choreoathetoid movements in cocaine dependence
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DOI:
10.1016/s0006-3223(98)00238-8
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发表时间:
1999-06-15
影响因子:
10.6
通讯作者:
Mintz, J
Mintz, J
中科院分区:
医学1区
文献类型:
--
作者:
Bartzokis, G;Beckson, M;Mintz, J

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背景:为了评估可卡因依赖者和年龄匹配的正常对照组的编舞类动作的严重程度,方法:采用异常不自主运动量表(AIMS)对71例可卡因依赖者、56名正常对照组和9名苯丙胺依赖者的编舞类动作进行评估。结果:可卡因依赖者的非面部(肢体+身体)AIMS分值显著增加,当两组的非面部AIMS分值与年龄的关系进行比较时,诊断交互作用显示出显著的年龄差异,表明两组之间的差异在较年轻的年龄组中最为显著。面部AIMS得分也有所增加,但仅在最年轻的CD队列中(32岁以下)。9名年轻的苯丙胺依赖者的AIMS得分也有所增加。结论:年轻的可卡因和苯丙胺依赖者的编舞类动作增加可能与其精神刺激剂的使用有关。老年CD受试者和正常对照受试者在编舞类动作上没有差异,可能代表了艺术年龄相关的自我选择效应。(C)1999年生物精神病学学会。
Background: To evaluate the severity of choreoathetoid movements in cocaine dependent (CD) subjects and age-matched normal control subjects,Methods: Choreoathetoid movements were evaluated using the Abnormal Involuntary Movement Scale (AIMS) in samples of 71 CD, 56 normal control, and 9 amphetamine-dependent male subjects.Results: The CD subjects had a significantly increased nonfacial (limbs plus body) AIMS subscore, When the nonfacial AIMS scores of the two groups were compared in relation to age, a significant age by diagnosis interaction was observed, indicating that the differences between groups were most marked in the younger age groups. The facial AIMS scores were also increased but only in the youngest CD cohort (under 32 years of age). The comparison group of 9 younger amphetamine-dependent subjects also showed increased AIMS scores.Conclusions: Increases in choreoathetoid movements in younger cocaine and amphetamine-dependent subjects may be related to their psychostimulant use. The absence of differences in choreoathetoid movements between the older CD subjects and normal control subjects may represent art age-related self-selection effect. (C) 1999 Society of Biological Psychiatry.