White blood cell subsets are associated with carotid intima-media thickness and pulse wave velocity in an older Chinese population: the Guangzhou Biobank Cohort Study

White blood cell subsets are associated with carotid intima-media thickness and pulse wave velocity in an older Chinese population: the Guangzhou Biobank Cohort Study
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DOI:
10.1038/jhh.2011.58
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发表时间:
2012-08-01
影响因子:
2.7
通讯作者:
Lam, T. H.
Lam, T. H.
中科院分区:
医学4区
文献类型:
--
作者:
Phillips, A. C.;Jiang, C. Q.;Lam, T. H.

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在一个新的中国老年社区样本中,研究了白色血细胞(WBC)计数、淋巴细胞和粒细胞数量与颈动脉内膜中层厚度(IMT)和臂踝脉搏波速度(PWV)之间的横断面相关性。来自广州生物样本库队列研究的一项子研究中,共有817名男性和760名女性通过自动血液分析仪测量全血细胞计数,通过B型超声检查测量颈动脉IMT,并通过无创自动波形分析仪测量臂踝PWV。校正混杂因素后,WBC计数(β = 0.07,P
Cross-sectional associations between white blood cell (WBC) count, lymphocyte and granulocyte numbers, and carotid intima-media thickness (IMT) and brachial-ankle pulse wave velocity (PWV) were examined in a novel older Chinese community sample. A total of 817 men and 760 women from a sub-study of the Guangzhou Biobank Cohort Study had a full blood count measured by an automated hematology analyzer, carotid IMT by B-mode ultrasonography and brachial-ankle PWV by a non-invasive automatic waveform analyzer. Following adjustment for confounders, WBC count (beta = 0.07, P