Mucinous adenocarcinomas of nose and paranasal sinuses
Mucinous adenocarcinomas of nose and paranasal sinuses
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鼻和鼻旁窦的粘液性腺癌
DOI：
10.1002/1097-0142(197509)36:3
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发表时间：
1975
期刊：
影响因子：
6.2
通讯作者：
MD G. Ayala
中科院分区：
文献类型：
--
作者：
MD I. J. GAMEZ;MD‘ ALBERTO G. AYALA;Oscar Guillamondegui MD’;MD G. Ayala
本文报告18例鼻和/或鼻窦粘液腺癌的临床病理资料。年龄在50岁以上的男性在该系列中占主导地位。鼻塞、鼻窦肿块或鼻衄是最常见的投诉。上颌窦肿瘤10例，鼻腔肿瘤5例。组织学上，肿瘤呈乳头状或实性。大多数乳头状肿瘤是中到高分化的，有少数低分化类型。实体性生长的肿瘤是间变性的，这些患者的预后较差。对于大多数患者，治疗包括单独的根治性手术或联合放疗。13例患者的生存率可以充分评估，7例死于肿瘤，5例存活4年以上，1例在诊断后14个月复发。
This study concerns the Clinicopathologic findings for 18 patients with mucinous adenocarcinomas of nose and/or paranasal sinuses. Males in the 5th decade of life predominated in the series. Nasal obstruction, a growing mass in a sinus, or epistaxis were the most frequent complaints. Ten patients had tumors in the maxillary antrum, and the nasal cavity was the site in 5 patients. Histopathologically, the tumors were papillary or solid. The majority of the papillary tumors were moderately to well differentiated, with a few poorly differentiated types. Tumors with the solid pattern of growth were anaplastic; these patients had poorer prognoses. For most patients, treatment consisted of radical surgery alone or in combination with radiotherapy. Of 13 patients for whom survival could be adequately evaluated, 7 died from the tumors, 5 are alive and free of disease more than 4 years, and 1 is living with recurrent tumor 14 months after diagnosis.