On the causes of melanomas.
On the causes of melanomas.
复制标题
关于黑色素瘤的原因。
DOI：
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发表时间：
1977
影响因子：
6
通讯作者：
A. Lerner
中科院分区：
文献类型：
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作者：
J. Nordlund;A. Lerner
大量的因素已经被确定，这些因素似乎使个体易患黑色素瘤。黑皮肤的人很少有恶性肿瘤，但这种肿瘤在红头发或金发的人身上很常见。如果这些皮肤白皙的人长时间暴露在强烈的阳光下，黑色素瘤的发病率会特别高。先天性或后天的痣可退化为黑色素瘤。在一些家庭中，许多家庭成员会长出多个痣，这些痣非常大，颜色是红色的。随着时间的推移，所有这些似乎都会退化成黑色素瘤。自然界提供了其他遗传因素诱发黑色素瘤的例子，即在月牙鱼和辛克莱微型猪中形成的黑色素瘤。
A large number of factors have been identified which seem to predispose an individual to develop melanoma. Black-skinned individuals rarely have malanomas, but this variety of tumors is common in red-haired or blond subjects. The incidence of melanoma is particularly high if such fair-skinned subjects are exposed for long perods of time to intense sunlight. Nevi, congenital or acquired, can degenerate into melanomas. In some families, many of the family members develop multiple nevi that are unusually large and red in color. All of these appear to degenerate into melanomas with time. Nature has provided other examples of genetic factors which induce melanomas, i.e., the melanomas which form in the platyfish and Sinclair miniature swine.