Discordance between self-reported arthritis and musculoskeletal signs and symptoms in older women.

Discordance between self-reported arthritis and musculoskeletal signs and symptoms in older women.
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DOI:
10.1186/s12891-016-1349-4
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发表时间:
2016-12-01
影响因子:
2.3
通讯作者:
Byles J
Byles J
中科院分区:
医学3区
文献类型:
--
作者:
Lo T;Parkinson L;Cunich M;Byles J

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关节炎是一种性别疾病,女性比同龄的关节炎男性患病率更高,残疾更多。健康调查数据是监测关节炎负担的主要信息来源。自我报告的关节炎的有效性及其在女性中准确性的决定因素尚未得到彻底研究。本研究的目的是:1)检查社区老年妇女自我报告诊断的关节炎与肌肉骨骼体征和症状之间的一致性; 2)估计自我报告关节炎的敏感性,特异性和预测值; 3)评估与分歧相关的因素。2012- 2013年对妇女进行了一次横断面调查。这项健康调查询问了女性被诊断为关节炎和肌肉骨骼的体征和症状。自我报告的关节炎和肌肉骨骼体征症状之间的一致性通过Cohen kappa来测量。使用肌肉骨骼体征和症状作为参考标准,评估自我报告关节炎的敏感性、特异性和预测值。与自我报告的关节炎和参考标准之间的分歧相关的因素进行了检查,使用多元逻辑回归。有223名参与者自我报告关节炎,347名没有。与那些没有报告关节炎的人相比,更多的自我报告关节炎的参与者是肥胖的。那些报告关节炎的人有更差的健康,身体功能和关节炎症状措施。在570名参与者中,198名有肌肉骨骼体征和症状提示关节炎(参考标准)。自我报告的关节炎与参考标准之间的一致性为中度(kappa = 0.41)。老年女性自我报告关节炎的敏感性、特异性、阳性和阴性预测值分别为66.7%、75.5%、59.2%和81.0%。回归分析结果表明,假阳性与更好的健康状况有关,这些健康状况由简明36表身体总分、健康评估问卷残疾指数或西安大略和麦克马斯特大学骨关节炎指数总分测量;而假阴性与这些变量呈负相关。虽然一些报告诊断为关节炎的妇女最近没有肌肉骨骼体征或症状,但其他有体征和症状的妇女没有报告诊断为关节炎。在流行病学研究中,研究人员在使用自我报告的关节炎作为病例定义时应谨慎。本文的在线版本(doi:10.1186/s12891-016-1349-4)包含补充材料,可供授权用户使用。
Arthritis is a gendered disease where women have a higher prevalence and more disability than men with arthritis of the same age. Health survey data is a major source of information for monitoring of the burden of arthritis. The validity of self-reported arthritis and the determinants of its accuracy among women have not been thoroughly studied. The objectives of this study were to: 1) examine the agreement between self-report diagnosed arthritis and musculoskeletal signs and symptoms in community-living older women; 2) estimate the sensitivity, specificity, and predictive values of self-reported arthritis; and 3) assess the factors associated with the disagreement. A cross-sectional survey of women was undertaken in 2012–13. The health survey asked women about diagnosed arthritis and musculoskeletal signs and symptoms. Agreement between self-reported arthritis and musculoskeletal signs symptoms was measured by Cohen’s kappa. Sensitivity, specificity, and predictive values of self-reported arthritis were estimated using musculoskeletal signs and symptoms as the reference standard. Factors associated with disagreement between self-reported arthritis and the reference standard were examined using multiple logistic regression. There were 223 participants self-reported arthritis and 347 did not. A greater number of participants who self-reported arthritis were obese compared to those who did not report arthritis. Those who reported arthritis had worse health, physical functioning, and arthritis symptom measures. Among the 570 participants, 198 had musculoskeletal signs and symptoms suggesting arthritis (the reference standard). Agreement between self-reported arthritis and the reference standard was moderate (kappa = 0.41). Sensitivity, specificity, and positive and negative predictive values of self-reported arthritis in older women were 66.7, 75.5, 59.2, and 81.0% respectively. Regression analysis results indicated that false-positive is associated with better health measured by the Short Form 36 physical summary score, the Health Assessment Questionnaire disability index, or the Western Ontario and McMaster University Osteoarthritis Index total score; whereas false-negative is negatively associated with these variables. While some women who reported diagnosed arthritis did not have recent musculoskeletal signs or symptoms, others with the signs and symptoms did not report diagnosed arthritis. Researchers should use caution when employing self-reported arthritis as the case-definition in epidemiological studies. The online version of this article (doi:10.1186/s12891-016-1349-4) contains supplementary material, which is available to authorized users.
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