Temporal lobe epilepsy semiology.
Temporal lobe epilepsy semiology.
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DOI：
10.1155/2012/751510
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发表时间：
2012
期刊：
影响因子：
--
通讯作者：
Blair RD
中科院分区：
文献类型：
--
作者：
Blair RD
癫痫是一组多层面的疾病，根据发作起始区可分为两大类，即部分性癫痫和全身性癫痫。确定癫痫发作起始的神经解剖部位依赖于通过详细病史以及视频脑电图，并结合多种神经影像学技术（如磁共振成像、功能磁共振成像、氟脱氧葡萄糖 - 正电子发射断层扫描、脑磁图或有创性颅内脑电图记录）对发作症状学的描述。颞叶癫痫是局灶性癫痫最常见的形式，几乎占手术治疗的难治性癫痫病例的三分之二。热性惊厥（尤其是复杂性热性惊厥）病史在颞叶癫痫中很常见，且常常与内侧颞叶硬化（颞叶癫痫最常见的形式）相关。许多颞叶癫痫患者会出现发作先兆，且常常表现出对颞叶癫痫相对特异的特征，但很少有定侧价值。然而，自动症往往具有定侧意义。仔细研究发作症状学在寻找发作起始区方面仍然具有极其重要的价值。
Epilepsy represents a multifaceted group of disorders divided into two broad categories, partial and generalized, based on the seizure onset zone. The identification of the neuroanatomic site of seizure onset depends on delineation of seizure semiology by a careful history together with video-EEG, and a variety of neuroimaging technologies such as MRI, fMRI, FDG-PET, MEG, or invasive intracranial EEG recording. Temporal lobe epilepsy (TLE) is the commonest form of focal epilepsy and represents almost 2/3 of cases of intractable epilepsy managed surgically. A history of febrile seizures (especially complex febrile seizures) is common in TLE and is frequently associated with mesial temporal sclerosis (the commonest form of TLE). Seizure auras occur in many TLE patients and often exhibit features that are relatively specific for TLE but few are of lateralizing value. Automatisms, however, often have lateralizing significance. Careful study of seizure semiology remains invaluable in addressing the search for the seizure onset zone.