Patterned adsorption of protein onto a carbohydrate monolayer immobilized on Si

Patterned adsorption of protein onto a carbohydrate monolayer immobilized on Si
复制标题

蛋白质在固定于 Si 上的碳水化合物单层上的图案化吸附

DOI:
10.1021/la0349020
复制
发表时间:
2003
期刊:
影响因子:
3.9
通讯作者:
K. Koumoto
K. Koumoto
中科院分区:
化学2区
文献类型:
--
作者:
N. Shirahata;T. Yonezawa;Y. Miura;A. K. Kobayashi;K. Koumoto

文献摘要

被引文献

相似文献

我们提出了一种制造碳水化合物末端单层(CM)表面的技术,该表面在埃水平上非常平坦。CM通过Si - C共价键固定在Si表面。在CM底物表面的CM区观察到接触溶液中蛋白质分子的特异性吸附,而在Si−O区观察到其非特异性吸附。
We propose a technique for fabricating a carbohydrate-terminated monolayer (CM) surface, which is extremely flat at the angstrom level. The CM was immobilized onto a Si surface by Si−C covalent bond. Specific adsorption of the protein molecule from a contacting solution was observed on the CM area of a patterned CM substrate surface, while its nonspecific adsorption was observed on the Si−O area.