Outcome of adults with sickle cell disease admitted to critical care - experience of a single institution in the UK
Outcome of adults with sickle cell disease admitted to critical care - experience of a single institution in the UK
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DOI：
10.1111/j.1365-2141.2010.08271.x
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发表时间：
2010-09-01
影响因子：
6.5
通讯作者：
Thein, Swee L.
中科院分区：
文献类型：
--
作者：
Gardner, Kate;Bell, Cathy;Thein, Swee L.
镰状细胞病（SCD）患者在重症监护室（CCU）的死亡率很高。我们对一个中心8年（2000年1月1日至2007年12月31日）内因镰状手术进入CCU的所有成人患者进行了回顾性分析。38例患者（14例男性）46次入住CCU;最常见的入院原因是急性胸部综合征（14例，30%）、多器官功能衰竭（8例，17%）和计划的择期手术后（7例，15%）。SCD患者的CCU死亡率为19中心点6%，与同一机构研究期间CCU范围内的死亡率17中心点6%相当。再次入住CCU的比例很高（8年内为16%），但并未增加死亡风险。
P>Sickle cell disease (SCD) patients are perceived to have a high mortality when admitted to the Critical Care Unit (CCU). We performed a retrospective analysis of all adult sickle admissions to CCU at a single centre over an 8-year period (1 January 2000 to 31 December 2007). Thirty-eight patients (14 male) were admitted 46 times to CCU; the commonest reasons for admission were acute chest syndrome (14, 30%), multi-organ failure (8, 17%) and planned post-elective surgery (7, 15%). CCU mortality for SCD patients was 19 center dot 6%, comparable to a CCU-wide mortality of 17 center dot 6% during the study period in the same institution. Re-admission to CCU was high (16% over the 8-year period) but did not increase mortality risk.