Salivary stress biomarker levels during speech in patients with maxillectomy defect.
Salivary stress biomarker levels during speech in patients with maxillectomy defect.
复制标题
上颌骨切除缺损患者言语过程中唾液应激生物标志物水平。
DOI:
10.1002/hed.21508
复制
发表时间:
2011
期刊:
影响因子:
--
通讯作者:
Minagi S
中科院分区:
文献类型:
--
作者:
Ugawa Y;Nishhigawa G;Maruo Y;Suwaki M;Minagi S
BackgroundAfter resection of maxillofacial tumors, severe functional problems related to mastication, deglutition, and speech are observed in addition to the changes in appearance and psychosocial functioning. Although speech outcome is recovered with prosthetic treatments, patients sometimes complain of continued dissatisfaction with their speech. The purpose of this study was to evaluate the potential dissatisfaction of patients with maxillectomy defects during speech.MethodsSixteen patients with maxillary obturator were compared with a matched control group. Functional improvement by the maxillofacial prosthesis was confirmed using a speech intelligibility test, a chewing function score, and visual analogue scale on subjective satisfaction. Cortisol and chromogranin A (CgA) were evaluated after prescribed speech tasks.ResultsCgA in patients with maxillectomy defects was significantly higher than that in the control group (p< .05), even after the functional improvement by maxillofacial prosthesis.ConclusionIt was revealed that patients with maxillectomy defects have significant psychological stresses during speech, even when their maxillofacial prosthesis resulted in successful functional improvement. © 2010 Wiley Periodicals, Inc. Head Neck, 2011