Continuous monitoring of cerebral hemodynamic reserve in acute brain injury: relationship to changes in brain swelling.
Continuous monitoring of cerebral hemodynamic reserve in acute brain injury: relationship to changes in brain swelling.
复制标题
急性脑损伤中脑血流动力学储备的连续监测：与脑肿胀变化的关系。
DOI：
10.1097/00005373-199205000-00015
复制
发表时间：
1992
期刊：
影响因子：
--
通讯作者：
Alves,WM
中科院分区：
文献类型：
--
作者：
Cruz,J;Gennarelli,TA;Alves,WM
脑血流动力学和代谢生理学的一个新概念，脑血流动力学储备（CED），在20例急性创伤性脑肿胀昏迷的成人中进行了评价，这些成人接受了持续监测动脉-颈静脉血氧饱和度差，沿着脑灌注压和呼气PCO 2。颅内压自发性升高时，脑氧摄取的相对变化（百分比）与脑灌注压的相对变化之比即为脑氧摄取的相对变化（百分比）。在最初严重脑肿胀的患者中，第一天的脑水肿更频繁地异常（受损），并在第二天趋于改善。在最初有中度脑肿胀的患者中，第一天的脑水肿通常是正常的（保留），但如果脑肿胀加剧，第二天往往会受到损害。它的结论是，脑血流动力学储备异常非常密切相关的迹象增加颅内“紧张”的头部计算机断层扫描。因此，脑血流动力学储备可能成为各种主要弥漫性急性颅内疾病中急性脑肿胀（侧重于脑氧合和灌注压）的功能评价和管理的重要指南。
A new concept of cerebral hemodynamic and metabolic physiology, cerebral hemodynamic reserve (CHR), was evaluated in 20 comatose adults with acute traumatic brain swelling who were undergoing continuous monitoring of the arteriojugular difference in oxyhemoglobin saturation, along with cerebral perfusion pressure and expired Pco 2. The CHR was measured as the ratio of relative (percent) changes in cerebral oxygen extraction to relative changes in cerebral perfusion pressure during spontaneous increases in intracranial pressure. In patients with initially severe brain swelling, the CHR was more frequently abnormal (compromised) on the first day, and tended to improve on the second day. In patients with initially moderate brain swelling, the CHR was more frequently normal (preserved) on the first day, but tended to become compromised on the second day if the brain swelling exacerbated. It is concluded that cerebral hemodynamic reserve abnormalities very closely associated with signs of increased intracranial “tightness” on computed tomographic scans of the head. Cerebral hemodynamic reserve could therefore become an important guide in the functional evaluation and management of acute brain swelling (focusing on cerebral oxygenation and perfusion pressure) in a variety of predominantly diffuse acute intracranial disorders.
持续运动过程中的力量发展：步态、速度和代谢能力的决定因素。
DOI：
10.1242/jeb.115.1.253
发表时间：
1985
期刊：
The Journal of experimental biology
影响因子：
--
作者：
Taylor,CR
通讯作者：
Taylor,CR