The relationship between ART adherence and smoking status among HIV+ individuals.
The relationship between ART adherence and smoking status among HIV+ individuals.
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DOI：
10.1007/s10461-014-0978-6
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发表时间：
2015-04
影响因子：
4.4
通讯作者：
Goggin K
中科院分区：
文献类型：
--
作者：
Moreno JL;Catley D;Lee HS;Goggin K
吸烟在HIV阳性个体中非常普遍，研究表明，吸烟可能与ART依从性差有关，尽管这种关系尚不清楚。此外，对有依从性困难的HIV+吸烟者的戒烟兴趣知之甚少。我们研究了203名HIV阳性个体的吸烟和ART依从性，这些个体参加了一项增加ART依从性的干预措施的随机试验。既往分析表明，无总体治疗组效应。在基线时评估吸烟状况和戒烟动机，并在第12、24、36和48周评估ART依从性。控制治疗组的纵向广义估计方程分析显示，随着时间的推移，吸烟状态与依从性无显著相关。戒烟的动机很高，58%的人打算在未来6个月内戒烟，25%的人打算在未来30天内戒烟。研究结果表明，吸烟是不相关的坚持那些坚持困难。然而，这并没有减少解决这两种行为的重要性，特别是考虑到艾滋病毒+吸烟者对改变吸烟行为的浓厚兴趣。
Smoking is highly prevalent among HIV+ individuals and studies indicate that it may be associated with poor ART adherence, though the relationship is poorly understood. In addition little is known about interest in quitting among HIV+ smokers who are having adherence difficulties. We examined smoking and ART adherence among 203 HIV+ individuals enrolled in a randomized trial of interventions to increase ART adherence. Prior analyses indicated there were no overall treatment group effects. Smoking status and motivation to quit was assessed at baseline and ART adherence was assessed at week 12, 24, 36, and 48. Longitudinal generalized estimating equation analysis that controlled for treatment group revealed that smoking status was not significantly related to adherence over time. Motivation to quit was high with 58% intending to quit in the next 6 months and 25% intending to quit in the next 30 days. Findings suggest that smoking is not associated with adherence among those with adherence difficulties. However it does not diminish importance of addressing both behaviors especially given HIV+ smokers substantial interest in changing smoking behavior.