STRUCTURAL BASIS FOR STATIC MECHANICAL PROPERTIES OF AORTIC MEDIA
STRUCTURAL BASIS FOR STATIC MECHANICAL PROPERTIES OF AORTIC MEDIA
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DOI：
10.1161/01.res.14.5.400
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发表时间：
1964-01-01
影响因子：
20.1
通讯作者：
GLAGOV, S
中科院分区：
文献类型：
--
作者：
WOLINSKY, H;GLAGOV, S
用光镜和电镜观察了家兔主动脉各结构成分的排列及其相互关系。主动脉中膜的胶原和弹性蛋白成分的机械性质和组织表明，主动脉壁通常作为“两相”材料发挥作用。在生理压力和生理压力以上，高拉伸强度和相对高弹性模量的周向排列的胶原纤维承受大部分应力。弹性模量相对较低的弹性蛋白层和原纤维均匀地分布应力。试图评估中间压力和张力梯度在主动脉疾病发病机制中的作用，必须考虑到这种“两相”材料的特殊机械性能。
The arrangement and interrelation of the structural components of the rabbit aorta were studied by light and electron microscopy. The mechanical properties and organization of the collagen and elastin components of the aortic media indicate that the wall normally functions as a "two-phase" material. At and above physiological pressures, circumferentially aligned collagen fibers of high tensile strength and relatively high modulus of elasticity bear most of the stressing force. Elastin lamellae and fibrils of relatively low modulus of elasticity distribute stressing forces uniformly. Attempts to assess the role of medial pressure and tension gradients in the pathogenesis of aortic disease must take into account the special mechanical properties of this "two-phase" material.