Expression of human MxA protein in mosquito cells interferes with LaCrosse virus replication.
Expression of human MxA protein in mosquito cells interferes with LaCrosse virus replication.
复制标题
蚊子细胞中人类 MxA 蛋白的表达会干扰君越病毒的复制。
DOI:
10.1128/jvi.75.6.3001-3003.2001
复制
发表时间:
2001
影响因子:
5.4
通讯作者:
Olson,KE
中科院分区:
文献类型:
--
作者:
Miura,TA;Carlson,JO;Beaty,BJ;Bowen,RA;Olson,KE
Human MxA protein inhibits LaCrosse virus (LAC virus; familyBunyaviridae) replication in vertebrate cells andMxA-transgenic mice. LAC virus is transmitted to humans byAedes triseriatusmosquitoes. In this report, we have shown that transfected mosquito cells expressing the humanMxAcDNA are resistant to LAC virus but permissive for Sindbis virus (familyTogaviridae) infection.