P3-420: AN EVENT BASED MODEL OF ALZHEIMER'S DISEASE IN APOE+ SUBJECTS USING ROBUST BIOMARKERS OF VOLUMETRIC CHANGE IN REGIONAL BRAIN STRUCTURE
P3-420: AN EVENT BASED MODEL OF ALZHEIMER'S DISEASE IN APOE+ SUBJECTS USING ROBUST BIOMARKERS OF VOLUMETRIC CHANGE IN REGIONAL BRAIN STRUCTURE
复制标题
P3-420：使用区域脑结构体积变化的鲁棒生物标志物建立 APOE 受试者阿尔茨海默病的基于事件的模型
DOI：
10.1016/j.jalz.2018.06.1783
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发表时间：
2018
期刊：
影响因子：
--
通讯作者：
Aksman L
中科院分区：
文献类型：
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作者：
Aksman L
背景• 已证明，至少具有一个 APOE4 等位基因 (APOE+) 的受试者患 AD1 的风险较高。我们对 APOE+ 受试者的 AD 疾病进展进行建模，因为与整个人群相比，他们可能是一个更加同质的队列。
Background• Subjects with at least one APOE4 allele (APOE+) have been shown to be at higher risk of developing AD1. We model AD disease progression in APOE+ subjects as they may serve as a more homogenous cohort compared to the whole population.