Presence and severity of non-alcoholic fatty liver disease in a large prospective primary care cohort
Presence and severity of non-alcoholic fatty liver disease in a large prospective primary care cohort
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DOI：
10.1016/j.jhep.2011.03.020
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发表时间：
2012-01-01
影响因子：
25.7
通讯作者：
Newsome, Philip N.
中科院分区：
文献类型：
--
作者：
Armstrong, Matthew J.;Houlihan, Diarmaid D.;Newsome, Philip N.
背景与目的：非酒精性脂肪性肝病(NAFLD)是初级保健中LFT异常的常见原因，但没有数据定义其作用，也没有报道NAFLD在这种情况下的严重程度。这项研究旨在计算初级保健环境中NAFLD的疾病严重程度范围。方法：从伯明翰的8家初级保健机构前瞻性招募无既往病史或当前肝病症状/体征的偶发异常LFTs的成年患者。非酒精性脂肪肝的超声诊断为脂肪肝，血清肝病原学筛查阴性，饮酒
Background & Aims: Non-alcoholic fatty liver disease (NAFLD) is a common cause of abnormal LFTs in primary care, but there are no data defining its contribution nor reporting the range of NAFLD severity in this setting. This study seeks to calculate the range of disease severity of NAFLD in a primary care setting.Methods: Adult patients with incidental abnormal LFTs, in the absence of a previous history, or current symptoms/ signs of liver disease were prospectively recruited from eight primary care practices in Birmingham. NAFLD was diagnosed as fatty liver on ultrasound, negative serological liver aetiology screen, and alcohol consumption