A Review on the Sex Differences in Organ and System Pathology with Alcohol Drinking.

A Review on the Sex Differences in Organ and System Pathology with Alcohol Drinking.
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DOI:
10.2174/1874473710666170125151410
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发表时间:
2016
期刊:
Current drug abuse reviews
影响因子:
--
通讯作者:
McClain CJ
McClain CJ
中科院分区:
其他
文献类型:
--
作者:
Vatsalya V;Liaquat HB;Ghosh K;Mokshagundam SP;McClain CJ

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饮酒的有害后果对整体健康,特别是身心健康造成不利影响。已经观察到男性和女性在饮酒和病理表现上的差异,但了解这些差异的研究有限。现在已经对饮酒的负面后果进行了研究,其中性行为是一个重要因素。一些研究表明,饮酒后果的严重程度在性别之间存在差异,包括精神后果和不同器官系统的变化/损伤。随着时间的推移,女性对饮酒的动态和饮酒的有害后果的报告有所增加,主要是因为更多的认识、更好的观察以及将性作为科学调查的一个因素。本文综述了性别差异在饮酒的病理生理和行为后果中的作用。
Hazardous consequences of alcohol consumption adversely influence overall health, specifically physical and mental health. Differences in alcohol consumption and manifestations in pathology have been observed between males and females, however research on understanding these differences is limited. Negative consequences of alcohol consumption have now been studied including sex as a significant factor. Some studies have shown differences in the severity of consequences of alcohol consumption between the sexes, both in the mental consequences and changes/ injury in various organ systems. Over time, reports in females on both the dynamics of drinking and on the hazardous consequences of alcohol consumption have grown, primarily because of more awareness, better observation, and the inclusion of sex as a factor in scientific investigations. This paper reviews role of sex differences in pathophysiological and behavioral consequences of alcohol drinking.