The Biomolecular Interaction Network Database and related tools 2005 update.

The Biomolecular Interaction Network Database and related tools 2005 update.
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DOI:
10.1093/nar/gki051
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发表时间:
2005-01-01
影响因子:
14.9
通讯作者:
Hogue CW
Hogue CW
中科院分区:
生物学2区
文献类型:
--
作者:
Alfarano C;Andrade CE;Anthony K;Bahroos N;Bajec M;Bantoft K;Betel D;Bobechko B;Boutilier K;Burgess E;Buzadzija K;Cavero R;D'Abreo C;Donaldson I;Dorairajoo D;Dumontier MJ;Dumontier MR;Earles V;Farrall R;Feldman H;Garderman E;Gong Y;Gonzaga R;Grytsan V;Gryz E;Gu V;Haldorsen E;Halupa A;Haw R;Hrvojic A;Hurrell L;Isserlin R;Jack F;Juma F;Khan A;Kon T;Konopinsky S;Le V;Lee E;Ling S;Magidin M;Moniakis J;Montojo J;Moore S;Muskat B;Ng I;Paraiso JP;Parker B;Pintilie G;Pirone R;Salama JJ;Sgro S;Shan T;Shu Y;Siew J;Skinner D;Snyder K;Stasiuk R;Strumpf D;Tuekam B;Tao S;Wang Z;White M;Willis R;Wolting C;Wong S;Wrong A;Xin C;Yao R;Yates B;Zhang S;Zheng K;Pawson T;Ouellette BF;Hogue CW

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生物分子相互作用网络数据库(BIND)(bind.ca)将生物分子相互作用、反应、复合物和途径信息存档。我们的目标是整理有关已发表的实验研究中产生的分子相互作用的详细信息,并向全球研究人员免费提供这些信息以及数据分析工具。BIND数据被整理成一个全面的机器可读的可计算信息档案,并为用户提供发现相互作用和分子机制的方法。BIND致力于开发新的可视化方法,以放大基因和蛋白质的潜在注释,从而促进分子相互作用网络的研究。BIND自1999年成立以来一直保持开放数据库政策。数据以惊人的速度增长,接近10万多条记录。提供的新服务包括新的BIND查询和提交界面、标准对象访问协议服务和小分子相互作用数据库(smid.blueprint.org),该数据库允许用户确定新序列的可能的小分子结合位点并检查保守的结合残基。
The Biomolecular Interaction Network Database (BIND) (http://bind.ca) archives biomolecular interaction, reaction, complex and pathway information. Our aim is to curate the details about molecular interactions that arise from published experimental research and to provide this information, as well as tools to enable data analysis, freely to researchers worldwide. BIND data are curated into a comprehensive machine-readable archive of computable information and provides users with methods to discover interactions and molecular mechanisms. BIND has worked to develop new methods for visualization that amplify the underlying annotation of genes and proteins to facilitate the study of molecular interaction networks. BIND has maintained an open database policy since its inception in 1999. Data growth has proceeded at a tremendous rate, approaching over 100 000 records. New services provided include a new BIND Query and Submission interface, a Standard Object Access Protocol service and the Small Molecule Interaction Database (http://smid.blueprint.org) that allows users to determine probable small molecule binding sites of new sequences and examine conserved binding residues.