Effect of 8-month vertical whole body vibration on bone, muscle performance, and body balance:: A randomized controlled study
Effect of 8-month vertical whole body vibration on bone, muscle performance, and body balance:: A randomized controlled study
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DOI：
10.1359/jbmr.2003.18.5.876
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发表时间：
2003-05-01
影响因子：
6.2
通讯作者：
Vuori, I
中科院分区：
文献类型：
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作者：
Torvinen, S;Kannus, P;Vuori, I
最近的动物研究证据表明，振动负荷可能是提高骨骼质量和机械能力的有效且安全的方法，从而为预防和治疗骨质疏松症提供了巨大的潜力。然而，缺乏关于振动对人体骨骼的安全性和有效性的随机对照试验。这项随机对照干预试验旨在评估为期 8 个月的全身振动干预对年轻和健康成年人的骨骼、肌肉性能和身体平衡的影响。 56 名志愿者（21 名男性和 35 名女性；年龄 19-38 岁）被随机分配到振动组或对照组。振动干预包括为期 8 个月的全身振动（每天 4 分钟，每周 3-5 次）。在 4 分钟的振动程序中，平台以 25 至 45 Hz 的升序振荡，对应于估计的最大垂直加速度从 2g 至 8g。在基线和 8 个月时通过外周定量计算机断层扫描 (pQCT) 评估远端胫骨和胫骨干的质量、结构和估计骨强度。在基线和 8 个月干预后，使用 DXA 测量腰椎、股骨颈、转子、跟骨和远端桡骨的骨矿物质含量。在基线以及第 3、6 和 8 个月时测定骨转换的血清标志物。在基线和 8 个月干预后进行了五项性能测试（垂直跳跃、下肢等长伸展力量、握力、往返跑和姿势摇摆）。为期 8 个月的振动干预取得了成功，并且可以安全执行，但对任何骨骼部位的质量、结构或估计骨骼强度没有影响。振动干预期间骨转换的血清标志物没有变化。然而，在 8 个月时，振动组的垂直跳跃高度净效益提高了 7.8%（95% CI，2.8-13.1%；p = 0.003）。在其他性能和平衡测试中，振动干预没有影响。总之，所研究的全身振动计划对年轻健康成年人的骨骼没有影响，但反而增加了垂直跳跃高度。在提出振动锻炼的临床建议之前，还需要进行未来的人体研究。
Recent animal studies have given evidence that vibration loading may be an efficient and safe way to improve mass and mechanical competence of bone, thus providing great potential for preventing and treating osteoporosis. Randomized controlled trials on the safety and efficacy of the vibration on human skeleton are, however, lacking. This randomized controlled intervention trial was designed to assess the effects of an 8-month whole body vibration intervention on bone, muscular performance, and body balance in young and healthy adults. Fifty-six volunteers (21 men and 35 women; age, 19-38 years) were randomly assigned to the vibration group or control group. The vibration intervention consisted of an 8-month whole body vibration (4 min/day, 3-5 times per week). During the 4-minute vibration program, the platform oscillated in an ascending order from 25 to 45 Hz, corresponding to estimated maximum vertical accelerations from 2g to 8g. Mass, structure, and estimated strength of bone at the distal tibia and tibial shaft were assessed by peripheral quantitative computed tomography (pQCT) at baseline and at 8 months. Bone mineral content was measured at the lumbar spine, femoral neck, trochanter, calcaneus, and distal radius using DXA at baseline and after the 8-month intervention. Serum markers of bone turnover were determined at baseline and 3, 6, and 8 months. Five performance tests (vertical jump, isometric extension strength of the lower extremities, grip strength, shuttle run, and postural sway) were performed at baseline and after the 8-month intervention. The 8-month vibration intervention succeeded well and was safe to perform but had no effect on mass, structure, or estimated strength of bone at any skeletal site. Serum markers of bone turnover did not change during the vibration intervention. However, at 8 months, a 7.8% net benefit in the vertical jump height was observed in the vibration group (95% CI, 2.8-13.1%; p = 0.003). On the other performance and balance tests, the vibration intervention had no effect. In conclusion, the studied whole body vibration program had no effect on bones of young, healthy adults, but instead, increased vertical jump height. Future human studies are needed before clinical recommendations for vibration exercise.