Detection of sympathoadrenal discharge by parameterisation of skin conductance and ECG measurement
Detection of sympathoadrenal discharge by parameterisation of skin conductance and ECG measurement
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通过皮肤电导参数化和心电图测量来检测交感肾上腺放电
DOI：
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发表时间：
2017
期刊：
影响因子：
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通讯作者：
Ø. Martinsen
中科院分区：
文献类型：
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作者：
C. Tronstad;O. Elvebakk;H. Kalvøy;Marit R. Bjorgaas;Ø. Martinsen
检测交感肾上腺放电对于压力监测很有价值，但直接测量循环肾上腺素水平并不方便，这使得非侵入性生理传感器成为一种有吸引力的替代方案。然而，人们对它们检测不同肾上腺素水平的性能知之甚少。在这项研究中，20 名受试者 × 2 次试验随时间的肾上腺素测量值与不同皮肤部位的皮肤电导 (SC) 以及从中得出心率和 QT 间期的心电图记录进行了比较。促汗反应 (FSR) 的频率源自 SC 记录，并针对不同皮肤部位的 FSR、心率和 QT 间期的不同组合计算出用于放大多个传感器信号同步变化的新复合参数。评估单一参数和复合参数对肾上腺素水平高于 1000、1500 和 2000 pmol/L 的检测性能。使用腹部 FSR、前额 FSR 和心率的复合参数显示出最佳预测性能，2000 pmol/L 阈值的 ROC 曲线下面积为 0.93。总之，在舒适的室温下的休息条件下，检测强交感肾上腺放电是可行的且具有良好的准确性。
Detection of sympathoadrenal discharge is valuable for stress monitoring, but measuring the circulating adrenaline level directly is inconvenient, making non-invasive physiological sensors an attractive alternative. Little is known however, about their performance in detecting different adrenaline levels. In this study, adrenaline measurements over time from 20 subjects × 2 trials were compared with skin conductance (SC) from different skin sites and ECG recordings from which the heart rate and QT interval were derived. The frequency of sudomotor responses (FSR) was derived from the SC recording, and a new composite parameter for amplification of synchronous changes in multiple sensor signals was calculated for different combinations of FSR from different skin sites, heart rate and QT interval. The single and composite parameters were evaluated for detection performance of adrenaline levels above 1000, 1500 and 2000 pmol/L. The best prediction performance was indicated for the composite parameter using the FSR from the abdomen, FSR from the forehead and the heart rate, with a ROC area under the curve of 0.93 for the 2000 pmol/L threshold. In conclusion, detection of strong sympathoadrenal discharges is feasible with good accuracy during resting conditions in comfortable room temperature.
葡萄糖对低血糖的反调节反应。
DOI：
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发表时间：
2011
期刊：
Pediatric endocrinology reviews : PER
影响因子：
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作者：
Sprague,JenniferE;Arbeláez,AnaMaría
通讯作者：
Arbeláez,AnaMaría