Linkage of the preimplantation-embryo-development (Ped) gene to the mouse major histocompatibility complex (MHC).
Linkage of the preimplantation-embryo-development (Ped) gene to the mouse major histocompatibility complex (MHC).
复制标题
植入前胚胎发育 (Ped) 基因与小鼠主要组织相容性复合体 (MHC) 的连锁。
DOI：
10.1095/biolreprod36.3.606
复制
发表时间：
1987
影响因子：
3.6
通讯作者：
Goldbard,SB
中科院分区：
文献类型：
--
作者：
Warner,CM;Gollnick,SO;Goldbard,SB
The preimplantation-embryo-development (Ped) gene influences the rate of cleavage division of preimplantation mouse embryos. The location of the Ped gene in the mouse major histocompatibility complex (MHC), the H-2 complex, has been inferred from the analysis of cleavage rates of embryos from mouse strains congenic at the H-2 complex. In this paper, formal genetic linkage studies were undertaken to evaluate linkage of the Ped gene to the H-2 complex. Co-segregation of Ped gene phenotype and H-2 haplotype was found in back-cross embryos. These data support the hypothesis that the Ped gene is linked to the H-2 complex.
