Selected applications of cyclodextrin selectors in capillary electrophoresis.
Selected applications of cyclodextrin selectors in capillary electrophoresis.
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环糊精选择器在毛细管电泳中的精选应用。
DOI：
10.1016/0021-9673(91)80072-o
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发表时间：
1991
期刊：
影响因子：
--
通讯作者：
Jelinek,I
中科院分区：
文献类型：
--
作者：
Snopek,J;Soini,H;Novotny,M;Smolkova-Keulemansova,E;Jelinek,I
通过使用α-、β-、γ-和七（2，6-二-O-甲基）-β-环糊精作为立体特异性选择剂或电解质调节剂，在毛细管区带电泳和等速电泳中，对选定的模型异构体化合物（包括光学异构体）进行了拆分。可溶性烷基羟烷基纤维素衍生物进一步加入到环糊精改性的背景电解质的研究。他们的存在被认为是必不可少的，证明了对映体选择性和分离效率的改善。在两种电泳模式下，在优化的条件下，得到的结果进行了比较和讨论。
Through the use of α-, β-, γ- and heptakis(2,6-di-O-methyl)-β-cyclodextrin as stereospecific selectors or electrolyte modifiers, both in capillary zone electrophoresis and isotachophoresis, selected model isomeric compounds (including optical isomers) were resolved. Soluble alkylhydroxyalkylcellulose derivatives were further added to the cyclodextrin-modified background electrolytes under study. Their presence was found to be essential, as demonstrated by improvements in both enantioselectivity and separation efficiency. The results obtained in both electrophoretic modes, under optimized conditions, are compared and discussed.