Comparison of two positive reinforcing stimuli: Pups and cocaine throughout the postpartum period
Comparison of two positive reinforcing stimuli: Pups and cocaine throughout the postpartum period
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DOI：
10.1037/0735-7044.115.3.683
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发表时间：
2001-06-01
影响因子：
1.9
通讯作者：
Morrell, JJ
中科院分区：
文献类型：
--
作者：
Mattson, BJ;Williams, S;Morrell, JJ
这组实验研究了母亲行为表现背后的食欲或动机过程。采用位置偏好范式来同时研究可卡因和幼崽对母亲的增强作用。泌乳母鼠。这些修改使作者能够评估哪种刺激（皮下注射 10 毫克/公斤可卡因或 3 只幼崽）具有最强的强化价值。在产后第 10 天和第 16 天，母鼠更喜欢可卡因提示相关的室。而在产后第 8 天进行测试的母鼠更喜欢与幼崽提示相关的室。总体而言，数据揭示了测试时的产后时期与对可卡因或幼崽表现出的偏好之间的相互作用。进一步的测试将研究每种刺激的食欲过程背后的神经回路。
This set of experiments investigated the appetitive or motivational processes underlying the performance of maternal behavior. The place preference paradigm was adapted to simultaneously investigate the reinforcing properties of cocaine and pups for maternal. lactating dams. These modifications allowed the authors to assess which stimulus, either a 10 mg/kg sc injection of cocaine or 3 pups, had the strongest reinforcing value. At Postpartum Days 10 and 16, the dams preferred the cocaine cue-associated chamber. whereas the dams tested at Postpartum Day 8 preferred the pup cue-associated chamber. Overall, the data revealed an interaction between the postpartum period at testing and the exhibited preference for cocaine or pups. Further testing will investigate the neural circuitry underlying the appetitive processes of each stimulus.