Fluoroglycoproteins: ready chemical site-selective incorporation of fluorosugars into proteins
Fluoroglycoproteins: ready chemical site-selective incorporation of fluorosugars into proteins
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DOI：
10.1039/c0cc01576h
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发表时间：
2010-01-01
影响因子：
4.9
通讯作者：
Davis, Benjamin G.
中科院分区：
文献类型：
--
作者：
Boutureira, Omar;D'Hooge, Francois;Davis, Benjamin G.
标记和修饰策略允许实际合成均一的氟化糖基氨基酸、多肽和在糖中带有氟标记的蛋白质，并允许获得直接放射性标记的([(18)F]-糖基)蛋白质的第一个例子。
A tag-and-modify strategy allows the practical synthesis of homogenous fluorinated glyco-amino acids, peptides and proteins carrying a fluorine label in the sugar and allows access to first examples of directly radiolabelled ([(18)F]-glyco)proteins.