Ion Transporter Gene Families as Physiological Targets of Natural Selection During Salinity Transitions in a Copepod
Ion Transporter Gene Families as Physiological Targets of Natural Selection During Salinity Transitions in a Copepod
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离子转运蛋白基因家族作为桡足类盐度转变过程中自然选择的生理目标
DOI：
10.1152/physiol.00009.2021
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发表时间：
2021
期刊：
影响因子：
8.4
通讯作者：
Lee, Carol Eunmi
中科院分区：
文献类型：
--
作者：
Lee, Carol Eunmi
盐度是构成地球生物多样性的一个关键因素。随着气候变化和物种入侵等人为变化，全球许多种群正面临着迅速而剧烈的盐度变化。对copepod deurytemora亲和物种复合体的研究表明，离子转运蛋白基因家族是淡水入侵过程中盐度适应的主要基因位点。实验室实验和野生种群基因组调查揭示了在独立盐度转变过程中全基因组基因表达的进化变化和自然选择的平行基因组特征。我们的研究结果表明，在原生范围内的平衡选择和特定离子转运体之间的上位相互作用可能有助于平行淡水适应。总的来说，这些研究为快速盐度变化中生理适应的进化机制提供了前所未有的见解。
Salinity is a key factor that structures biodiversity on the planet. With anthropogenic change, such as climate change and species invasions, many populations are facing rapid and dramatic changes in salinity throughout the globe. Studies on the copepodEurytemora affinisspecies complex have implicated ion transporter gene families as major loci contributing to salinity adaptation during freshwater invasions. Laboratory experiments and population genomic surveys of wild populations have revealed evolutionary shifts in genome-wide gene expression and parallel genomic signatures of natural selection during independent salinity transitions. Our results suggest that balancing selection in the native range and epistatic interactions among specific ion transporter paralogs could contribute to parallel freshwater adaptation. Overall, these studies provide unprecedented insights into evolutionary mechanisms underlying physiological adaptation during rapid salinity change.