Oral manifestations of pediatric vertical HIV infection
Oral manifestations of pediatric vertical HIV infection
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DOI：
10.1089/108729100318028
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发表时间：
2000-02-01
影响因子：
4.9
通讯作者：
Kline, MW
中科院分区：
文献类型：
--
作者：
Kozinetz, CA;Carter, AB;Kline, MW
为了评估人类免疫缺陷病毒（HIV）感染儿童口腔表现史的患病率和预后意义，对73例垂直HIV感染儿童进行了队列研究。研究对象每6个月检查一次口腔表现。口腔表现的时期患病率范围从下颌下肥大的1%和毛状白斑的3%到口干症的36%和颈部淋巴结病的51%。1995年至1998年，口腔表现的发生率没有明显变化。最后，在6-18个月内诊断出颈部淋巴结病、口腔干燥症和口腔念珠菌病的儿童中，这些表现的发生率高于先前未诊断的儿童。口腔表现是儿科垂直HIV感染的重要临床结局，特别是对于先前诊断为口腔表现的儿童。
To assess the prevalence and prognostic significance of the history of oral manifestations in children with human immunodeficiency virus infection (HIV), a cohort study of 73 children with vertical HIV infection was conducted. The study subjects were examined every 6 months for oral manifestations. The period prevalence of oral manifestations ranged from a low of 1% for submandibular enlargement and 3% for hairy leukoplakia to a high of 36% for xerostomia and 51% for cervical lymphadenopathy. The occurrence of oral manifestations did not change significantly over time from 1995 to 1998. Finally, the odds of occurrence of cervical lymphadenopathy, xerostomia, and oral candidiasis were greater among children in whom these manifestations had been diagnosed in the preceding 6-18 months than in children without prior diagnosis. Oral manifestations are significant clinical outcomes in pediatric vertical HIV infection, particularly for children diagnosed previously with an oral manifestation.