Social and economic burden of mood disorders
Social and economic burden of mood disorders
复制标题
DOI：
10.1016/s0006-3223(03)00420-7
复制
发表时间：
2003-08-01
影响因子：
10.6
通讯作者：
Simon, GE
中科院分区：
文献类型：
--
作者：
Simon, GE
情绪障碍的社会和经济影响包括功能障碍、残疾或工作效率下降，以及医疗服务的使用增加。这些影响的证据包括横断面研究、纵向研究和真实实验（特定治疗或治疗方案的随机试验）。关于单相抑郁症，强有力的证据表明，抑郁症与严重的功能障碍有关，有效的治疗有助于恢复功能。关于抑郁症对工作障碍和医疗保健费用影响的研究显示了强烈的横截面关联（即，抑郁症患者的残疾程度更高，费用更高）和纵向关联（即，抑郁症的改善与减少残疾和降低成本有关）。所有这些关于单相抑郁症的研究结果在共病慢性医学疾病患者亚组中似乎与抑郁症总人群中一致。关于双相情感障碍的社会和经济负担的数据较少，但现有数据显示情绪症状与功能障碍，残疾和医疗保健费用之间存在横截面关联。总之，这些数据描述了情绪障碍的巨大社会和经济负担以及更有效治疗的潜在益处。然而，我们必须回顾，与减轻人类痛苦这一主要目标相比，治疗情绪障碍的经济效益是次要的。(C)2003生物精神病学学会。
Social and economic effects of mood disorders include functional impairment, disability or lost work productivity, and increased use of health services. Evidence for these impacts includes cross-sectional studies, longitudinal studies, and true experiments (randomized trials of specific treatments or treatment programs). With respect to unipolar depression, strong evidence demonstrates that depression is associated with significant functional impairment and that effective treatment helps to restore function. Studies of the effect of depression on work disability and health care costs show strong cross-sectional associations (i.e., greater disability and higher costs among those with depression) and longitudinal associations (i.e., improvement in depression is associated with reduced disability and lower costs). All of these findings regarding unipolar depression seem as consistent in the subgroup of patients with comorbid chronic medical illness as in the total population with depressive disorders. Fewer data are available regarding social and economic burden of bipolar disorder, but available data show cross-sectional associations between mood symptoms and functional impairment, disability, and health care costs. Taken together, these data describe the substantial social and economic burden of mood disorders and the potential benefits of more effective treatment. We must recall, however, that economic benefits of treatment for mood disorders are secondary to the principal objective of relieving human suffering. (C) 2003 Society of Biological Psychiatry.