Predictors of cough-specific and generic quality of life in sarcoidosis patients.
Predictors of cough-specific and generic quality of life in sarcoidosis patients.
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DOI：
10.36141/svdld.v37i2.9234
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发表时间：
2020
期刊：
影响因子：
--
通讯作者：
Maric NB
中科院分区：
文献类型：
--
作者：
Gvozdenovic BS;Mihailovic-Vucinic VV;Vukovic MH;Stjepanovic MI;Buha I;Mihailovic SV;Maric NB
咳嗽是结节病的常见症状，但其对患者生活质量的影响尚未得到充分的研究。本研究的目的是确定结节病患者咳嗽特异性和一般生活质量的重要预测因素。在这项前瞻性研究中，275名结节病患者接受了患者报告结果测量工具，用于测量呼吸困难（Borg和MRC量表）和疲劳（疲劳评估量表（FAS）和每日活动清单（DAL）），以及患者的生活质量（咳嗽特异性莱斯特咳嗽问卷（LCQ）和通用工具- 15D）。LCQ包括慢性咳嗽的生理、心理和社会三个方面。同时测定肺功能（肺活量测定和一氧化碳弥散能力）和血清血管紧张素转换酶（sACE）。Borg量表测量的呼吸困难和DAL仪测定的日常活动障碍以及sACE是所有咳嗽特异性生活质量域的最强预测因子。患者疲劳心理方面除与心理LCQ领域显著相关外，与其他各领域均显著相关。对于一般生活质量，以下显著预测因子为：MRC量表测量的呼吸困难，FAS测定的整体疲劳和LCQ的物理域。测量结节病患者咳嗽特异性和一般的生活质量是很重要的，因为它们测量不同的健康方面，它们的预测因素可能不同。我们证明了咳嗽特异性生活质量的物理域是通用生活质量的重要预测因子。（血管性弥漫性肺结节病2020；37 (2):158-168）
Cough is frequent symptom in sarcoidosis and its impact on patient’s quality of life (QoL) has not been adequately addressed so far. The goal of this study was to determine the significant predictors of cough-specific and generic QoL in sarcoidosis patients. In the prospective study 275 sarcoidosis patients administered Patient Reported Outcomes instruments for measurement of dyspnea (Borg and MRC scales) and fatigue (Fatigue Assessment Scale (FAS) and Daily Activity List (DAL)), as well as patients’ QoL (cough-specific Leicester Cough Questionnaire (LCQ) and generic tool – 15D). The LCQ contains 3 domains covering physical, psychological and social aspects of chronic cough. Pulmonary function tests (spirometry and diffusing capacity for carbon monoxide) and serum angiotensin converting enzyme (sACE) were also measured. Dyspnea measured by Borg scale and impairment of daily activities determined by DAL instrument as well as sACE were the strongest predictors of all cough-specific QoL domains. Mental aspect of patients’ fatigue was significantly correlated with all domains except with psychological LCQ domain. Regarding the generic QoL, the following significant predictors were: dyspnea measured by MRC scale, overall fatigue determined by FAS and physical domain of the LCQ. It is important to measure both cough-specific and generic QoL in sarcoidosis patients since they measure different health aspects and their predictors can be different. We demonstrated that physical domain of cough-specific QoL is significant predictor of generic QoL. (Sarcoidosis Vasc Diffuse Lung Dis 2020; 37 (2): 158-168)
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DOI：
10.5588/ijtld.14.0195
发表时间：
2014-12-01
影响因子：
4
作者：
Gao, Y-H.;Guan, W-J.;Chen, R-C.
通讯作者：
Chen, R-C.
DOI：
10.4168/aair.2015.7.3.230
发表时间：
2015-05
期刊：
Allergy, asthma & immunology research
影响因子：
--
作者：
Kwon JW;Moon JY;Kim SH;Song WJ;Kim MH;Kang MG;Lim KH;Lee SH;Lee SM;Lee JY;Kwon HS;Kim KM;Kim SH;Kim SH;Jeong JW;Kim CW;Cho SH;Lee BJ;Work Group for Chronic Cough, the Korean Academy of Asthma, Allergy and Clinical Immunology
通讯作者：
Work Group for Chronic Cough, the Korean Academy of Asthma, Allergy and Clinical Immunology
影响因子：
5
作者：
Judson, Marc A.;Chopra, Amit;Yucel, Recai M.
通讯作者：
Yucel, Recai M.
DOI：
10.1249/00005768-198205000-00012
发表时间：
1982-01-01
期刊：
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
影响因子：
--
作者：
BORG, GAV
通讯作者：
BORG, GAV
影响因子：
9.6
作者：
Krasowski, Matthew D.;Savage, Johanna;Genzen, Jonathan R.
通讯作者：
Genzen, Jonathan R.