One-step, safe synthesis of 2,4-dinitrostyrene and related (Di)nitrodivinylbenzenes via Stille coupling
One-step, safe synthesis of 2,4-dinitrostyrene and related (Di)nitrodivinylbenzenes via Stille coupling
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DOI：
10.1055/s-2008-1032117
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发表时间：
2008-06-02
影响因子：
2.6
通讯作者：
Poullain, Didier
中科院分区：
文献类型：
--
作者：
Eloy, Nathalie;Pasquinet, Eric;Poullain, Didier
介绍了一步法合成2,4-二硝基苯乙烯的方法。基于Stille耦合，与需要较长反应序列和危险硝化过程的现有方法相比，该方法更易于扩大规模。用连续萃取法分离了这种易聚合的单体。该反应扩展到合成另外两种相关的乙烯基单体，包括先前未知的1,3-二硝基-4,6-二乙烯基苯二烯。
A one-step synthesis of 2,4-dinitrostyrene is described. Based on a Stille coupling, the procedure is more amenable to scale-up than the existing methods that require longer reaction sequences and hazardous nitration processes. This easily polymerizable monomer was isolated using a continuous extraction method. The reaction was extended to the synthesis of two other related vinyl monomers including the previously unknown 1,3-dinitto-4,6-divinylbetizene.